INPP5J
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Official Full Name
inositol polyphosphate-5-phosphatase J
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Overview
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A is an enzyme that in humans is encoded by the INPP5J gene. -
Synonyms
INPP5J; inositol polyphosphate-5-phosphatase J; phosphatidylinositol (4,5) bisphosphate 5 phosphatase, A , PIB5PA; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; INPP5; inositol polyphosphate 5-phosphatase J; phosphatidylinositol (4,5) bisphosphat;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | INPP5J-2741H | Recombinant Human INPP5J Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | INPP5J-2395H | Recombinant Human INPP5J Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Mouse | INPP5J-8230M | Recombinant Mouse INPP5J Protein | Mammalian Cell | His | ||
Mouse | INPP5J-4558M | Recombinant Mouse INPP5J Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | INPP5J-4558M-B | Recombinant Mouse INPP5J Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Inpp5j-3549M | Recombinant Mouse Inpp5j Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Rat | INPP5J-3074R | Recombinant Rat INPP5J Protein | Mammalian Cell | His | ||
Rat | INPP5J-2730R-B | Recombinant Rat INPP5J Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | INPP5J-2730R | Recombinant Rat INPP5J Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
- Involved Pathway
- Protein Function
- Interacting Protein
INPP5J involved in several pathways and played different roles in them. We selected most pathways INPP5J participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with INPP5J were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Inositol phosphate metabolism | PLCE1;MINPP1A;INPP1;NUDT10;NUDT3A;INPPL1;PLCD3A;MINPP1B;MTMR3 |
Metabolic pathways | OXSR1;URAH;GLCE;G6PCA.1;IDUA;NME1;B4GALT3;NAT8L;ybaS |
Phosphatidylinositol signaling system | INPP5D;PRKCB;PIP5K1BB;DGKE;CALM1B;PIK3R3B;ITPKC;MTMR7B;INPP4AB |
INPP5J has several biochemical functions, for example, SH3 domain binding, hydrolase activity, inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INPP5J itself. We selected most functions INPP5J had, and list some proteins which have the same functions with INPP5J. You can find most of the proteins on our site.
Function | Related Protein |
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SH3 domain binding | KHDRBS3;ARHGAP1;NCKIPSD;SH3BGRL;SH3BP5B;PAK3;INPP5J;ELMO2;RAD9A |
hydrolase activity | UGT1AB;FAM108C;PRSS30;NOTS;MRPL46;SERHL2;DPYSL2B;TMPRSS13B;MPPED2 |
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity | INPP5A;INPP5J;INPP5K |
inositol-1,4,5-trisphosphate 5-phosphatase activity | INPP5J;INPP5A;INPP5B;INPP5K |
inositol-polyphosphate 5-phosphatase activity | INPPL1;INPP5D;INPP5A;INPP5K;INPP5J;INPP5E |
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity | INPP5K;INPP5J |
INPP5J has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INPP5J here. Most of them are supplied by our site. Hope this information will be useful for your research of INPP5J.
- Q&As
- Reviews
Q&As (7)
Ask a questionThe interaction between miR-661 and INPP5J enhances cell proliferation, promoting tumor growth in ovarian cancer.
The INPP5J-induced AKT pathway is associated with promoting cell proliferation in ovarian cancer, making it a significant factor in disease progression.
INPP5J is targeted by miR-661 and is involved in regulating the AKT pathway, contributing to cell proliferation in ovarian cancer.
MiR-661 directly targets INPP5J, likely resulting in reduced INPP5J expression.
The provided information doesn't specify the cellular localization of INPP5J in ovarian cancer cells.
Targeting INPP5J or its interaction with miR-661 could be explored as a potential therapeutic strategy for ovarian cancer.
INPP5J likely influences the AKT pathway, but the specific molecular mechanisms were not detailed in the provided information.
Customer Reviews (3)
Write a reviewIt met stringent safety standards, allowing us to work with confidence in a controlled laboratory environment.
The product's durability allowed us to confidently plan experiments without concerns about degradation.
We appreciated the ongoing assistance from the company, which contributed to the product's success in our experiments.
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