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INPPL1
Official Full Name
inositol polyphosphate phosphatase-like 1
Background
The protein encoded by this gene is an SH2-containing 5-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
Synonyms
INPPL1; inositol polyphosphate phosphatase-like 1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2; 51C protein; SHIP2; EC 3.1.3.n1; inositol polyphosphate phosphatase like 1; Inositol polyphosphate phosphatase like protein 1; Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2; Protein 51C; SH2 domain containing inositol 5 phosphatase 2; SH2 domain-containing inositol phosphatase 2; SHIP-2; INPPL-1; OTTHUMP00000237158; OTTHUMP00000237159; SH2 domain-containing inositol-5-phosphatase 2