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INTS8

Official Full Name

integrator complex subunit 8
Overview

INTS8 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large;subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2;(RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).
Synonyms

INTS8; integrator complex subunit 8; C8orf52, chromosome 8 open reading frame 52; FLJ20530; INT8; MGC131633; C8orf52; Chromosome 8 open reading frame 52; INTS 8; KAONASHI protein 1; KAONASHI1; protein kaonashi-1;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	INTS8-8252M	Recombinant Mouse INTS8 Protein	Mammalian Cell	His	Inquiry
Mouse	INTS8-4572M	Recombinant Mouse INTS8 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	INTS8-4572M-B	Recombinant Mouse INTS8 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	INTS8-2896Z	Recombinant Zebrafish INTS8	Mammalian Cell	His	Inquiry
Chicken	INTS8-3410C	Recombinant Chicken INTS8	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

INTS8 involved in several pathways and played different roles in them. We selected most pathways INTS8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with INTS8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

INTS8 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by INTS8 itself. We selected most functions INTS8 had, and list some proteins which have the same functions with INTS8. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	CFDP1;HIST1H2BA;WSCD2;SZT2;C11orf58;WAPALB;TMEM263;HYI;LRIG2

INTS8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INTS8 here. Most of them are supplied by our site. Hope this information will be useful for your research of INTS8.