IPMK
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Official Full Name
inositol polyphosphate multikinase
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Overview
This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19. -
Synonyms
IPMK; inositol polyphosphate multikinase; Inositol 1,3,4,6 tetrakisphosphate 5 kinase; 3; 4; 6-tetrakisphosphate 5-kinase; Inositol 1; IPMK_HUMAN; inositol 1,3,4,6-tetrakisphosphate 5-kinase;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
IPMK involved in several pathways and played different roles in them. We selected most pathways IPMK participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with IPMK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | MTM1;PLCB4;MTMR6;PIP5K1C;PIKFYVE;SYNJ1;PIK3CA;PLD4;PLCB3 |
| Metabolic pathways | HPSE;ATP5F1;PIGA;HYAL2;NDUFB7;CYP1A;PGS1;ADH2-2;PAPSS1 |
| Phosphatidylinositol signaling system | MTMR2;INPPL1;INPP5L;PIK3C3;TMEM55B;IP6K1;ITPR1;PLCG2;PIKFYVE |
IPMK has several biochemical functions, for example, ATP binding, inositol tetrakisphosphate 3-kinase activity, inositol-1,4,5-trisphosphate 3-kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IPMK itself. We selected most functions IPMK had, and list some proteins which have the same functions with IPMK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | SLC22A5;GATC;MYO6B;EPHA2;RUNX2B;CAMK1GB;GRK7B;UBE2H;ABCC3 |
| inositol tetrakisphosphate 3-kinase activity | |
| inositol-1,4,5-trisphosphate 3-kinase activity | IPMK;IP6K3;ITPKB;IPMKB;ITPKA;IP6K1;IP6K2;ITPKC |
| inositol-1,4,5-trisphosphate 6-kinase activity |
IPMK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IPMK here. Most of them are supplied by our site. Hope this information will be useful for your research of IPMK.
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