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IPO8

Official Full Name

importin 8
Synonyms

IPO8; importin 8; importin-8; Imp 8; Imp8; Importin8; IPO 8; Ran binding protein 8; RAN BP8; RANBP 8; RANBP8;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|GST

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	IPO8-5075H	Recombinant Human IPO8 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	IPO8-8266M	Recombinant Mouse IPO8 Protein	Mammalian Cell	His		Inquiry
Mouse	Ipo8-199M	Recombinant Mouse Ipo8 Protein, His/GST-tagged	E.coli	His/GST	Tyr417~Val622	Inquiry
Mouse	IPO8-4583M	Recombinant Mouse IPO8 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	IPO8-4583M-B	Recombinant Mouse IPO8 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	IPO8-2286R	Recombinant Rhesus monkey IPO8 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	IPO8-2107R-B	Recombinant Rhesus Macaque IPO8 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	IPO8-2107R	Recombinant Rhesus Macaque IPO8 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	IPO8-3874Z	Recombinant Zebrafish IPO8	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
IPO8 Related Articles

IPO8 involved in several pathways and played different roles in them. We selected most pathways IPO8 participated on our site, such as Gene Expression, Gene Silencing by RNA, Transcriptional regulation by small RNAs, which may be useful for your reference. Also, other proteins which involved in the same pathway with IPO8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	SNRNP48;C22orf28;RNPC3;APOBEC1;HBXIP;TRMT112;ZNF41;COX14;PTRFB
Gene Silencing by RNA	TDRD1;PLD6;EIF2C3;PIWIL4;TNRC6B;TARBP2;BARHL1;TSNAX;HENMT1
Transcriptional regulation by small RNAs	IPO8;DPY19L2

IPO8 has several biochemical functions, for example, ATPase activity, coupled to transmembrane movement of substances, Ran GTPase binding, protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IPO8 itself. We selected most functions IPO8 had, and list some proteins which have the same functions with IPO8. You can find most of the proteins on our site.

Function	Related Protein
ATPase activity, coupled to transmembrane movement of substances	ABCA9;ABCB1;Abca2;ABCA1;ABCB10;ABCC2;ABCG5;ABCC8;DPY19L2
Ran GTPase binding	KPNB1;BIRC5;XPO7;XPOT;RANBP3;NUP153;XPO4;IPO13;RANGRF
protein transporter activity	AP1S3;AP3S1;DPY19L2;PPIAL4A;ARFGAP3;L7RN6;RAP1A;VPS26BL;KPNA5

IPO8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IPO8 here. Most of them are supplied by our site. Hope this information will be useful for your research of IPO8.

Irs1; Rpgrip1l

Moriyama, T; Mizuguchi, C; et al. Generation of Rat Monoclonal Antibody Specific for Mouse Importin alpha 8. HYBRIDOMA 30:303-306(2011).

Yoneda, Y; et al. Monoclonal Antibody 3F2 Against Mouse Importin alpha 8. HYBRIDOMA 30:315-315(2011).

Pryor, MJ; Rawlinson, SM; et al. Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection. TRAFFIC 8:795-807(2007).

Subramaniam, PS; Larkin, J; et al. The COOH-terminal nuclear localization sequence of interferon gamma regulates STAT1 alpha nuclear translocation at an intracellular site. JOURNAL OF CELL SCIENCE 113:2771-2781(2000).