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Official Full Name
IQ motif containing GTPase activating protein 1
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
IQGAP1; IQ motif containing GTPase activating protein 1; ras GTPase-activating-like protein IQGAP1; HUMORFA01; KIAA0051; p195; RasGAP like with IQ motifs; SAR1; IQGA1_HUMAN; Ras GTPase activating like protein 1; RasGAP-like with IQ motifs