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IQGAP3

  • Official Full Name

    IQ motif containing GTPase activating protein 3

  • Synonyms

    IQGAP3; IQ motif containing GTPase activating protein 3; ras GTPase-activating-like protein IQGAP3; IQGA3_HUMAN; IQGAP 3; MGC10170; MGC10831; MGC1947; OTTHUMP00000031854; OTTHUMP00000031855; Ras GTPase activating like protein IQGAP3;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IQGAP3-869HCL Recombinant Human IQGAP3 cell lysate N/A
Human IQGAP3-5060H Recombinant Human IQGAP3 Protein, GST-tagged Wheat Germ GST
Human IQGAP3-2562H Recombinant Human IQGAP3 protein, His-tagged E.coli His 530-880 aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein

IQGAP3 involved in several pathways and played different roles in them. We selected most pathways IQGAP3 participated on our site, such as CDC42 signaling events, RAC1 signaling pathway, RHO GTPase Effectors, which may be useful for your reference. Also, other proteins which involved in the same pathway with IQGAP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
CDC42 signaling eventsARPC2;EPS8;CDC42BPA;CFL1;ACTR2;BAIAP2;IQGAP3;ACTR3;ARPC1B
RAC1 signaling pathwayBAIAP2;ABI2;IQGAP3;NCKAP1;ABI1;NOXO1;RACGAP1;NOXA1
RHO GTPase EffectorsMKL1B;KNTC1;TAX1BP3;PRC1;EVL;WASF3;RHOGA;IQGAP3;RHPN2
RHO GTPases activate IQGAPs
Regulation of actin cytoskeletonNCKAP1L;RDX;PIP5K1AB;ITGA11A;PIK3R1;VAV3;BAIAP2A;GNA13A;PAK2B
Signal TransductionCD97;OTULINB;RAMP3;KIDINS220B;KLHL12;NOXO1;RTN4;EVC2;JUPA
Signaling by Rho GTPasesARHGAP22;STARD8;RHOT1B;FAM13B;ARHGAP23;ARHGAP15;NOXO1A;GMIP;TAGAP

IQGAP3 has several biochemical functions, for example, GTPase activator activity, Rho GTPase binding, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IQGAP3 itself. We selected most functions IQGAP3 had, and list some proteins which have the same functions with IQGAP3. You can find most of the proteins on our site.

Function Related Protein
GTPase activator activityTBC1D5;ADAP2;ARHGAP15;RIN1;TBC1D10B;ARHGAP5;GIT2B;RASAL3;TBC1D1
Rho GTPase bindingDOCK9;RHOH;IQGAP3;DOCK11;ROCK2;DIAPH3;INF2;DAPK3;PARD6A
calmodulin bindingARPP21;MKNK2B;SNTB2;SCN5A;RYR3;STRN;C2orf62;RASGRF2;GRIN1
myosin VI light chain binding

IQGAP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IQGAP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of IQGAP3.

Ndc80; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; PTBP3; MYC; CDC42; Smn1; IQCB1; LRRK2; Kctd5

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