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IRAK1
Official Full Name
interleukin-1 receptor-associated kinase 1
Background
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
IRAK1; interleukin-1 receptor-associated kinase 1; IRAK; pelle; EC 2.7.11.1; Pelle homolog