Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

IRGM

  • Official Full Name

    immunity-related GTPase family, M

  • Overview

    This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohns disease and tuberculosis.
  • Synonyms

    IRGM; immunity-related GTPase family, M; immunity related GTPase family, M1 , IRGM1; immunity-related GTPase family M protein; IFI1; LRG 47; LRG47; LRG-47-like protein; interferon-inducible protein 1; immunity-related GTPase family, M1; LPS-stimulated RAW;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IRGM-394H Recombinant Human immunity-related GTPase family, M, His-tagged E.coli His
Human IRGM-5030H Recombinant Human IRGM Protein, GST-tagged Wheat Germ GST
Human IRGM-3118H Recombinant Human IRGM protein, GST-tagged E.coli GST 1-181aa
Rat IRGM-3098R Recombinant Rat IRGM Protein Mammalian Cell His
Rat IRGM-2754R Recombinant Rat IRGM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat IRGM-2754R-B Recombinant Rat IRGM Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IRGM Related Articles

IRGM involved in several pathways and played different roles in them. We selected most pathways IRGM participated on our site, such as Toxoplasmosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IRGM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ToxoplasmosisHLA-DRB5;BIRC3;HSPA1L;SOCS1;IL10RB;IRAK1;MAPK3;NOS2;PIK3R3

IRGM has several biochemical functions, for example, GTP binding, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IRGM itself. We selected most functions IRGM had, and list some proteins which have the same functions with IRGM. You can find most of the proteins on our site.

Function Related Protein
GTP bindingARF4A;IRGE4;GNA14;GUCY2C;ERCC3;SEPT5B;ARL4D;ARL4A;ARHGAP35
hydrolase activityRAG1;RNASEKB;NDST2;GZME;IRGM;PTPRFB;MMP23BB;CASP3A;CTDNEP1A

IRGM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IRGM here. Most of them are supplied by our site. Hope this information will be useful for your research of IRGM.

Ciccacci, C; Perricone, C; et al. A Multilocus Genetic Study in a Cohort of Italian SLE Patients Confirms the Association with STAT4 Gene and Describes a New Association with HCP5 Gene. PLOS ONE 9:-(2014).
Lee, KM; Lee, JM; et al. Crohn's disease in Korea: past, present, and future. KOREAN JOURNAL OF INTERNAL MEDICINE 29:558-570(2014).
Murdoch, TB; Xu, W; et al. Pattern recognition receptor and autophagy gene variants are associated with development of antimicrobial antibodies in Crohn's disease. INFLAMMATORY BOWEL DISEASES 18:1743-1748(2012).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All IRGM Products

Required fields are marked with *

My Review for All IRGM Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends