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IST1

Official Full Name

increased sodium tolerance 1 homolog (yeast)
Overview

This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms

MGC117220; IST1; increased sodium tolerance-1; Putative MAPK-activating protein PM28; IST1 homolog; hIST1; KIAA0174; OTTHUMP00000174931; OTTHUMP00000174932; OTTHUMP00000238707; OTTHUMP00000238709; increased sodium tolerance 1 homolog (yeast);

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	IST1-13789H	Recombinant Human IST1, GST-tagged	E.coli	GST	1-364a.a.	$319 / 25ug
Human	IST1-62H	Recombinant Human IST1 protein, His-tagged	E.coli	His	350aa(including fusion tag)	Inquiry
Human	IST1-358HCL	Recombinant Human IST1 lysate	HEK293	N/A		Inquiry
Human	IST1-5769HF	Recombinant Full Length Human IST1 Protein, GST-tagged	In Vitro Cell Free System	GST	366 amino acids	Inquiry
Human	IST1-5009H	Recombinant Human IST1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	IST1-8337M	Recombinant Mouse IST1 Protein	Mammalian Cell	His		Inquiry
Mouse	IST1-4627M	Recombinant Mouse IST1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	IST1-4627M-B	Recombinant Mouse IST1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	IST1-3107R	Recombinant Rat IST1 Protein	Mammalian Cell	His		Inquiry
Rat	IST1-2763R	Recombinant Rat IST1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	IST1-2763R-B	Recombinant Rat IST1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	IST1-11864Z	Recombinant Zebrafish IST1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
IST1 Related Articles

IST1 involved in several pathways and played different roles in them. We selected most pathways IST1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Endocytosis	SNX4;ZFYVE9;ARRB2;PARD6GA;SNX1A;SH3GL1A;CDC42L;EGFRA;SH3GL3

IST1 has several biochemical functions, for example, MIT domain binding, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IST1 itself. We selected most functions IST1 had, and list some proteins which have the same functions with IST1. You can find most of the proteins on our site.

Function	Related Protein
MIT domain binding
protein binding	LGALS1;HTRA3;LIN7A;DNTTIP1;TAF1D;GSE1;pab1;HORMAD1;ZNF295
protein complex binding	GNB1;NCK2;TELO2;PLK2;BAX;ARRB2;HADHA;NR0B2;SH2B3
protein domain specific binding	CSNK2B;TFDP2;RQCD1;YWHAH;ZNF521;HIST1H4E;DICER1;ARFIP2B;ARFIP2

IST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IST1.

CAPN7; APEH; CAPN7; UBQLN1; ATXN1; q7ard3_yerpe; pi3p

Shao, Q; Han, N; et al. SsHKT1;1 is a potassium transporter of the C-3 halophyte Suaeda salsa that is involved in salt tolerance. FUNCTIONAL PLANT BIOLOGY 41:790-802(2014).

Gasparic, MB; Lenassi, M; et al. Insertion of a Specific Fungal 3 '-phosphoadenosine-5 '-phosphatase Motif into a Plant Homologue Improves Halotolerance and Drought Tolerance of Plants. PLOS ONE 8:-(2013).