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ITGB1BP1

Official Full Name

integrin beta 1 binding protein 1
Overview

The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.
Synonyms

ITGB1BP1; integrin beta 1 binding protein 1; integrin beta-1-binding protein 1; bodenin; ICAP 1A; ICAP 1alpha; ICAP 1B; ICAP1; ICAP1A; ICAP1B; integrin cytoplasmic domain associated protein 1; integrin cytoplasmic domain associated protein 1 alpha; integrin cytoplasmic domain associated protein 1 beta; DKFZp686K08158; ICAP 1; ICAP-1; Integrin cytoplasmic domain-associated protein 1; ITBP1_HUMAN; OTTHUMP00000115481; OTTHUMP00000115482; OTTHUMP00000195584; OTTHUMP00000195586; OTTHUMP00000214081; OTTHUMP00000214082; OTTHUMP00000214088; integrin cytoplasmic dom; ICAP-1A; ICAP-1B; ICAP-1alpha;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ITGB1BP1-177H	Recombinant Human ITGB1BP1, GST-tagged	E.coli	GST	8-200aa	$319 / 25ug
Human	ITGB1BP1-5126HCL	Recombinant Human ITGB1BP1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	ITGB1BP1-2647H	Recombinant Human ITGB1BP1 Protein, His-tagged	E.coli	His		Inquiry
Human	ITGB1BP1-4985H	Recombinant Human ITGB1BP1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ITGB1BP1-5761HF	Recombinant Full Length Human ITGB1BP1 Protein, GST-tagged	In Vitro Cell Free System	GST	200 amino acids	Inquiry
Mouse	ITGB1BP1-8362M	Recombinant Mouse ITGB1BP1 Protein	Mammalian Cell	His		Inquiry
Mouse	ITGB1BP1-4643M	Recombinant Mouse ITGB1BP1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	ITGB1BP1-4643M-B	Recombinant Mouse ITGB1BP1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	ITGB1BP1-3530Z	Recombinant Zebrafish ITGB1BP1	Mammalian Cell	His		Inquiry
Chicken	ITGB1BP1-5316C	Recombinant Chicken ITGB1BP1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ITGB1BP1 Related Articles
ITGB1BP1 Related Research Area

ITGB1BP1 involved in several pathways and played different roles in them. We selected most pathways ITGB1BP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGB1BP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ITGB1BP1 has several biochemical functions, for example, GDP-dissociation inhibitor activity, integrin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGB1BP1 itself. We selected most functions ITGB1BP1 had, and list some proteins which have the same functions with ITGB1BP1. You can find most of the proteins on our site.

Function	Related Protein
GDP-dissociation inhibitor activity	GPSM1;RGS14;GPSM2L;ITGB1BP1;SH3BP4A;RANBP1;SH3BP4;GPSM1B;GDI1
integrin binding	NISCH;PPAP2B;ADAM10;FCER2;IGF1;S1PR3;LYN;NIPAL1;FN1A
protein binding	ACTA1;CDH23;ZCCHC7;C19orf25;KREMEN1;TBC1D22B;TRPS1;NCDN;USP6
protein complex binding	AKAP5;CDH2;ARRB2;RAN;CAV3;NDUFA9;KAT6B;RIPK1;FBLN1
protein kinase binding	MLKL;MAPT;STK11IP;GSK3B;DVL1;ACVRL1;AGAP2;KAT2B;SLC12A7
protein transporter activity	AP1B1;RANGRF;IPO11;MLC1;RANBP6;RAMP1;IPO5;TIMM10;KPNA6

ITGB1BP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGB1BP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGB1BP1.

pgrmc1; FIGNL1; KRIT1; DFNA5; UTRN; EEF1A1; SLC35F5; FAF1

Wang, XZ; Maynard, JA; et al. The Bordetella Adenylate Cyclase Repeat-in-Toxin (RTX) Domain Is Immunodominant and Elicits Neutralizing Antibodies. JOURNAL OF BIOLOGICAL CHEMISTRY 290:3576-3591(2015).

Green, CJ; Fraser, ST; et al. Insulin-like growth factor 1 increases apical fibronectin in blastocysts to increase blastocyst attachment to endometrial epithelial cells in vitro. HUMAN REPRODUCTION 30:284-298(2015).

Immunoglobulin Superfamily CAMs