Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

IWS1

Official Full Name

IWS1 homolog
Overview

Various steps in gene expression, such as mRNA processing, surveillance, export, and synthesis are coupled to transcription elongation. The C-terminal domain (CTD) of the large subunit of RNA polymerase II plays an important role in the integration of the
Synonyms

IWS1; IWS1 homolog (S. cerevisiae); protein IWS1 homolog; DKFZp761G0123; FLJ10006; FLJ14655; FLJ32319; IWS1-like protein; interacts with Spt6; MGC126375; MGC126376;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	IWS1-5852HF	Recombinant Full Length Human IWS1 Protein, GST-tagged	In Vitro Cell Free System	GST	819 amino acids	Inquiry
Human	IWS1-4939H	Recombinant Human IWS1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	IWS1-0395H	Recombinant Human IWS1 protein, His-tagged	E.coli	His	523-819 aa	$319 / 25ug
Mouse	IWS1-8400M	Recombinant Mouse IWS1 Protein	Mammalian Cell	His		Inquiry
Mouse	IWS1-4662M-B	Recombinant Mouse IWS1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	IWS1-4662M	Recombinant Mouse IWS1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	IWS1-3131R	Recombinant Rat IWS1 Protein	Mammalian Cell	His		Inquiry
Rat	IWS1-2787R-B	Recombinant Rat IWS1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	IWS1-2787R	Recombinant Rat IWS1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
IWS1 Related Articles

IWS1 involved in several pathways and played different roles in them. We selected most pathways IWS1 participated on our site, such as Proteasome Degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with IWS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Proteasome Degradation	ASB2;UBR1;SPSB4;LRRC41;UBE2U;RNF182;SPSB2;UBE2V1;TRIM69

IWS1 has several biochemical functions, for example, peptidase activity, protein binding, ubiquitin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IWS1 itself. We selected most functions IWS1 had, and list some proteins which have the same functions with IWS1. You can find most of the proteins on our site.

Function	Related Protein
peptidase activity	HPN;HE1B;TMPRSS4A;FAM108A1;C6AST4;HTRA1A;GZMC;MEP1A.2;UCHL3
protein binding	SYF2;SEC22C;FNBP4;ATP7A;CD3E;MEOX1;SPOPL;DAAM1;APOE
ubiquitin binding	NUP62;BRAP;MARK4;DNAJC2;TOP2A;UBXN1;SPRTN;UCHL1;D17WSU92E
ubiquitin-specific protease activity	USP30;OTUD7B;JOSD2;USP15;USP28;VCPIP1;USP22;EIF3F;USP17L2

IWS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IWS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IWS1.

Ywhae

Gerard, A; Segeral, E; et al. The Integrase Cofactor LEDGF/p75 Associates with Iws1 and Spt6 for Postintegration Silencing of HIV-1 Gene Expression in Latently Infected Cells. CELL HOST & MICROBE 17:107-117(2015).

Wang, XL; Chen, JN; et al. Histone Lysine Methyltransferase SDG8 Is Involved in Brassinosteroid-Regulated Gene Expression in Arabidopsis thaliana. MOLECULAR PLANT 7:1303-1315(2014).