Your Position: Home
>> JPH2
JPH2
Official Full Name
junctophilin 2
Background
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.
Synonyms
JPH2; junctophilin 2; junctophilin-2; JP 2; FLJ40969; JP-2; JP2; JPH2_HUMAN; Junctophilin type 2; OTTHUMP00000031651; OTTHUMP00000031652; CMH17