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JUNB

  • Official Full Name

    jun B proto-oncogene

  • Overview

    The JunB transcrIPPtion factor, also known as JunB proto-oncogene, JunB oncogene, transcrIPPtion factor JunB, and transforming protein JunB, is a basic region leucine zIPPer DNA-binding protein, and a member of the Jun family of proteins, which also inclu
  • Synonyms

    JUNB; jun B proto-oncogene; transcription factor jun-B; activator protein 1; AP-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human JUNB-218H Recombinant Human JUNB, GST-tagged E.coli GST 1-200aa
Human JUNB-886HCL Recombinant Human JUNB cell lysate N/A
Human JUNB-2947H Recombinant Human JUNB protein, His-tagged E.coli His 1-200 aa
Human JUNB-294HFL Active Recombinant Full Length Human JUNB Protein, C-Flag-tagged Mammalian cells Flag
Human JUNB-1232H Recombinant Human JUNB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human JUNB-2074H Recombinant Human JUNB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human JUNB-1232H-B Recombinant Human JUNB Protein Pre-coupled Magnetic Beads HEK293
Mouse JUNB-8439M Recombinant Mouse JUNB Protein Mammalian Cell His
Mouse Junb-1253M Recombinant Mouse Junb Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse JUNB-4694M-B Recombinant Mouse JUNB Protein Pre-coupled Magnetic Beads HEK293
Mouse JUNB-4694M Recombinant Mouse JUNB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat JUNB-3147R Recombinant Rat JUNB Protein Mammalian Cell His
Rat JUNB-2803R Recombinant Rat JUNB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat JUNB-2803R-B Recombinant Rat JUNB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque JUNB-2336R Recombinant Rhesus monkey JUNB Protein, His-tagged Mammalian Cell His
Rhesus Macaque JUNB-2157R-B Recombinant Rhesus Macaque JUNB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque JUNB-2157R Recombinant Rhesus Macaque JUNB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • JUNB Related Articles

JUNB involved in several pathways and played different roles in them. We selected most pathways JUNB participated on our site, such as ATF-2 transcription factor network, Calcineurin-regulated NFAT-dependent transcription in lymphocytes, Calcium signaling in the CD4+ TCR pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with JUNB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ATF-2 transcription factor networkDUSP10;MAPK14;JUNB;KAT5;CDK4;KCNA3;POU2F1;DUSP5;DUSP1
Calcineurin-regulated NFAT-dependent transcription in lymphocytesPOU2F1;CTLA4;CDK4;EGR3;IRF4;BATF3;EGR4;JUNB;EGR1
Calcium signaling in the CD4+ TCR pathwayPOU2F1;FKBP1A;AKAP5;JUNB;RCAN1;BATF3;CHP;RCAN2;CSF2
Corticotropin-releasing hormoneCRH;KRT14;PARP1;IVL;CYP11B1;CRHBP;JUNB;TCF4;ADRBK2
Downstream signaling in naive CD8+ T cellsEGR4;EGR1;JUNB;EOMES
Gene ExpressionZMAT5;ZNF155;ZNF143B;APOBEC1;DDX6;PRDX2;XPOT;USP9;ZNF496
Generic Transcription PathwayZNF230;TACO1;ZIM2;ZNF615;TBX5;ZNF189;ZNF383;TEAD3B;ZNF625
IL6-mediated signaling eventsLMO4;PIAS3;CRP;JUNB

JUNB has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JUNB itself. We selected most functions JUNB had, and list some proteins which have the same functions with JUNB. You can find most of the proteins on our site.

Function Related Protein
DNA bindingDACH2;GM239;ETV5;ZNF184;ZNF670;ZFP110;SRFA;TAL2;HOXA5
RNA polymerase II core promoter proximal region sequence-specific DNA bindingBCL11A;MYOG;HELT;FOXD1;SMAD4;ELF3;MYF6;PITX3;NEUROD6
RNA polymerase II transcription factor activity, sequence-specific DNA bindingBHLHE40;FOXI3A;FOXJ1B;MITFB;MITFA;LMO2;SPI1;FOXI2;FOXI3B
protein bindingPIK3CD;PTI;GLE1;SCNN1B;NMU;C8orf48;HAX1;FAM50B;LRP2
transcription coactivator activityTCF3;MED31;CITED2;SIX3;GTF2A1;PPARGC1A;PRMT2;BIRC2;JUPA
transcription corepressor activityCBFA2T3;KCTD1;LOXL2;SSX1;DAXX;LMCD1;SP100;CIR1;SKOR1
transcription factor bindingTFDP2;JUNBA;CXXC5;CTBP1;TAF12;TP53;TAF7L;CAMTA2;NFKB1
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingFLI1;MZF1;HNF1A;PPARA;POU3F2;GLI3;MYB;GATA3;HIF1A

JUNB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JUNB here. Most of them are supplied by our site. Hope this information will be useful for your research of JUNB.

FOS; BATF; FOS; ATF2; FOSL2

Atsaves, V; Lekakis, L; et al. The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK plus anaplastic large cell lymphoma. BRITISH JOURNAL OF HAEMATOLOGY 167:514-523(2014).
Perdomo, MF; Hosia, W; et al. Human serum protein enhances HIV-1 replication and up-regulates the transcription factor AP-1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:17639-17644(2012).
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