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KCNE4

  • Official Full Name

    potassium voltage-gated channel, Isk-related family, member 4

  • Overview

    Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus.
  • Synonyms

    KCNE4; potassium voltage-gated channel, Isk-related family, member 4; potassium voltage-gated channel subfamily E member 4; MiRP3; Minimum potassium ion channel related peptide 3; MinK related peptide 3; Potassium channel subunit beta MiRP3; Potassium voltage gated channel subfamily E member 4; OTTHUMP00000203809; MINK-related peptide 3; minimum potassium ion channel-related peptide 3; cardiac voltage-gated potassium channel accessory subunit 4;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNE4-5063HCL Recombinant Human KCNE4 293 Cell Lysate HEK293 N/A
Mouse KCNE4-8494M Recombinant Mouse KCNE4 Protein Mammalian Cell His
Mouse KCNE4-4729M-B Recombinant Mouse KCNE4 Protein Pre-coupled Magnetic Beads HEK293
Mouse KCNE4-4729M Recombinant Mouse KCNE4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish KCNE4-5272Z Recombinant Zebrafish KCNE4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

KCNE4 involved in several pathways and played different roles in them. We selected most pathways KCNE4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNE4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

KCNE4 has several biochemical functions, for example, ion channel binding, protein binding, voltage-gated potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNE4 itself. We selected most functions KCNE4 had, and list some proteins which have the same functions with KCNE4. You can find most of the proteins on our site.

Function Related Protein
ion channel bindingGRINA;EPN1;RANGRF;USP10;CAV1;FKBP1B;KCNE1L;CALM2;PANX1
protein bindingFAH;CCDC47;CCR3;WBP11;XCL2;NQO1;RPP30;RAB10;Itga10&Itgb1
voltage-gated potassium channel activityKCNV2B;KCNC2;KCNE4;CNGA2;KCNAB1A;KCNMA1;CNGA3;KCNG4A;KCNA6A

KCNE4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNE4 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNE4.

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