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KCNK7

  • Official Full Name

    potassium channel, subfamily K, member 7

  • Overview

    This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    KCNK7; potassium channel, subfamily K, member 7; potassium channel subfamily K member 7; K2p7.1; TWIK3; Two pore domain K+ channel; potassium channel, subfamily K, member 7, isoform B;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNK7-5030HCL Recombinant Human KCNK7 293 Cell Lysate HEK293 N/A
Human KCNK7-5031HCL Recombinant Human KCNK7 293 Cell Lysate HEK293 N/A
Human KCNK7-5029HCL Recombinant Human KCNK7 293 Cell Lysate HEK293 N/A
Homo sapiens (Human) RFL28940HF Recombinant Full Length Human Potassium Channel Subfamily K Member 7(Kcnk7) Protein, His-Tagged E.coli expression system His Full Length (1-307)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KCNK7 Related Articles

KCNK7 involved in several pathways and played different roles in them. We selected most pathways KCNK7 participated on our site, such as Neuronal System, Potassium Channels, Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK), which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNK7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuronal SystemKCNA10;KCNH2A;KCNH6A;KCNK18;PPFIA2;KCNA2B;Apba1;KCNJ14;PANX2
Potassium ChannelsKCND1;KCNC2;KCNAB1;KCNMB2;KCNH1B;KCNC3A;KCNN1A;KCNC1;KCNN2
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)KCNK6;KCNK1A;KCNK7;KCNK1B;KCNK1
Tandem pore domain potassium channelsKCNK10B;KCNK2;DDX1;KCNK2B;KCNK7;KCNK16;KCNK1A;KCNK4;KCNK18

KCNK7 has several biochemical functions, for example, potassium channel activity, potassium ion leak channel activity, voltage-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNK7 itself. We selected most functions KCNK7 had, and list some proteins which have the same functions with KCNK7. You can find most of the proteins on our site.

Function Related Protein
potassium channel activityKCNK1A;KCNK5;KCNK3A;KCNC1A;ABCC9;KCNC3B;KCNC2;KCNK10B;KCNV2B
potassium ion leak channel activityKCNK5;KCNK7;KCNK1A;KCNK1B;TMEM175;DDX1;KCNK5A;KCNK10;KCNK5B
voltage-gated ion channel activityKCNC2;CACNG1A;CYBB;TMEM109;CLIC5A;TMEM37;CALHM1;KCNK10;KCNJ11L

KCNK7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNK7 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNK7.

Vetter, I; Hein, A; et al. Amplified Cold Transduction in Native Nociceptors by M-Channel Inhibition. JOURNAL OF NEUROSCIENCE 33:16627-16641(2013).
Zhang, J; Zhao, ZL; et al. Atrial natriuretic peptide modulates the proliferation of human gastric cancer cells via KCNQ1 expression. ONCOLOGY LETTERS 6:407-414(2013).
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