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KCNN3

  • Official Full Name

    potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

  • Overview

    KCNN3 forms one of several calcium-activated potassium channels which are activated in a voltage-independent manner and have a relatively small unit conductance and high sensitivity to intracellular calcium. Activation is followed by membrane hyperpolariz
  • Synonyms

    KCNN3; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3; small conductance calcium-activated potassium channel protein 3; hSK3; KCa2.3; SKCA3; SKCa 3; SK3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Sus scrofa (Pig)
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNN3-28455TH Recombinant Human KCNN3 Wheat Germ N/A 110 amino acids
Human KCNN3-5021HCL Recombinant Human KCNN3 293 Cell Lysate HEK293 N/A
Rat KCNN3-3220R Recombinant Rat KCNN3 Protein Mammalian Cell His
Rat KCNN3-2876R Recombinant Rat KCNN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KCNN3-2876R-B Recombinant Rat KCNN3 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL5239HF Recombinant Full Length Human Small Conductance Calcium-Activated Potassium Channel Protein 3(Kcnn3) Protein, His-Tagged E.coli expression system His Full Length (1-736)
Mus musculus (Mouse) RFL15172MF Recombinant Full Length Mouse Small Conductance Calcium-Activated Potassium Channel Protein 3(Kcnn3) Protein, His-Tagged E.coli expression system His Full Length (1-731)
Rattus norvegicus (Rat) RFL18835RF Recombinant Full Length Rat Small Conductance Calcium-Activated Potassium Channel Protein 3(Kcnn3) Protein, His-Tagged E.coli expression system His Full Length (1-732)
Sus scrofa (Pig) RFL5078SF Recombinant Full Length Pig Small Conductance Calcium-Activated Potassium Channel Protein 3(Kcnn3) Protein, His-Tagged E.coli expression system His Full Length (1-724)
  • Involved Pathway
  • Protein Function
  • Interacting Protein

KCNN3 involved in several pathways and played different roles in them. We selected most pathways KCNN3 participated on our site, such as Ca2+ activated K+ channels, Insulin secretion, Neuronal System, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ca2+ activated K+ channelsKCNMA1;KCNN4;KCNN2;KCNMB2;KCNN1B;KCNN3;KCNMB1;KCNN1A;KCNN1
Insulin secretionPLCB4;GNA11;PDX1;GIP;CREB3L3;KCNJ11;KCNMA1;GLP1R;ATP1A4
Neuronal SystemKCNQ2;HCN4;SLC6A12;KCNV2;SNAP25A;PANX2;SLC17A7A;KCNJ1A.1;KCNB2
Potassium ChannelsKCNQ3;KCNA1;KCNG3;KCNS3;KCNK4;KCNH5A;KCNJ1A.2;KCNMB1;KCNH1A

KCNN3 has several biochemical functions, for example, calmodulin binding, small conductance calcium-activated potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNN3 itself. We selected most functions KCNN3 had, and list some proteins which have the same functions with KCNN3. You can find most of the proteins on our site.

Function Related Protein
calmodulin bindingKCNN1B;MAPKAPK5;MAP6;MYO1F;MYH4;EDF1;MYLK;CAMK1D;KCNN1
small conductance calcium-activated potassium channel activityKCNN2;KCNN3;KCNN1;KCNN1A;KCNN1B

KCNN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNN3.

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