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Official Full Name
potassium voltage-gated channel, subfamily Q, member 2
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability.The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
KCNQ2; potassium voltage-gated channel, KQT-like subfamily, member 2; EBN, EBN1; potassium voltage-gated channel subfamily KQT member 2; BFNC; ENB1; HNSPC; KCNA11; Kv7.2; EBN 1; EBN; EBN1; ENB 1; KCNA 11; KCNQ 2; KQT like 2; KVEBN 1; KVEBN1; KvLQT 2; KvLQT2; Neuroblastoma specific potassium channel alpha subunit KvLQT2; Neuroblastoma specific potassium channel protein; Neuroblastoma specific potassium channel subunit alpha; Neuroblastoma specific potassium channel subunit alpha KvLQT2; OTTHUMP00000031681; OTTHUMP00000031682; OTTHUMP00000031684; OTTHUMP00000031685; OTTHUMP00000031686; OTTHUMP00000031687; OTTHUMP00000031689; Potassium voltage gated channel KQT like protein 2; Potassium voltage gated channel KQT like subfamily member 2; Potassium voltage gated channel subfamily KQT member 2; Voltage gated potassium channel subunit Kv7.2; KQT-like 2; voltage-gated potassium channel subunit Kv7.2; neuroblastoma-specific potassium channel protein; neuroblastoma-specific potassium channel subunit alpha KvLQT2; BFNS1; EIEE7