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KCNS1

  • Official Full Name

    potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1

  • Overview

    Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family.
  • Synonyms

    KCNS1; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1; potassium voltage-gated channel subfamily S member 1; Kv9.1; Delayed rectifier K(+) channel alpha subunit 1; Delayed-rectifier K(+) channel alpha subunit 1; K+ voltage gated channel, subfamily S, 1; KCNS1_HUMAN; OTTHUMP00000031783; potassium voltage gated channel delayed rectifier protein; potassium voltage gated channel delayed rectifier protein S1; potassium voltage gated channel, delayed rectifier, subfamily S, member 1; voltage gated potassium channel protein Kv9.1; Voltage gated potassium channel subunit Kv9.1; Voltage-gated potassium channel subunit Kv9.1; delayed-rectifier K+ channel alpha subunit 1; voltage-gated potassium channel protein Kv9.1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Aotus nancymaae (Ma's night monkey)
  • Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
  • Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey)
  • Gorilla gorilla gorilla (Western lowland gorilla)
  • Homo sapiens (Human)
  • Lemur catta (Ring-tailed lemur)
  • Macaca mulatta (Rhesus macaque)
  • Mouse
  • Mus musculus (Mouse)
  • Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
  • Pan troglodytes (Chimpanzee)
  • Papio anubis (Olive baboon)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse KCNS1-8550M Recombinant Mouse KCNS1 Protein Mammalian Cell His
Mouse KCNS1-4758M Recombinant Mouse KCNS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse KCNS1-4758M-B Recombinant Mouse KCNS1 Protein Pre-coupled Magnetic Beads HEK293
Rat KCNS1-3224R Recombinant Rat KCNS1 Protein Mammalian Cell His
Rat KCNS1-2880R Recombinant Rat KCNS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KCNS1-2880R-B Recombinant Rat KCNS1 Protein Pre-coupled Magnetic Beads HEK293
Aotus nancymaae (Ma's night monkey) RFL32044AF Recombinant Full Length Aotus Nancymaae Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-529)
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) RFL26401CF Recombinant Full Length Chlorocebus Aethiops Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-529)
Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey) RFL15494CF Recombinant Full Length Colobus Guereza Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-529)
Gorilla gorilla gorilla (Western lowland gorilla) RFL3915GF Recombinant Full Length Gorilla Gorilla Gorilla Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-526)
Homo sapiens (Human) RFL2068HF Recombinant Full Length Human Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-526)
Lemur catta (Ring-tailed lemur) RFL14954LF Recombinant Full Length Lemur Catta Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-529)
Macaca mulatta (Rhesus macaque) RFL19283MF Recombinant Full Length Macaca Mulatta (Rhesus Macaque) Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-529)
Mus musculus (Mouse) RFL12772MF Recombinant Full Length Mouse Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-497)
Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby) RFL27264OF Recombinant Full Length Otolemur Garnettii Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-528)
Pan troglodytes (Chimpanzee) RFL36703PF Recombinant Full Length Pan Troglodytes Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-526)
Papio anubis (Olive baboon) RFL21985PF Recombinant Full Length Papio Anubis Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-529)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL11711PF Recombinant Full Length Pongo Abelii Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-526)
Rattus norvegicus (Rat) RFL33484RF Recombinant Full Length Rat Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-497)
Rhesus Macaque KCNS1-2368R Recombinant Rhesus monkey KCNS1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque KCNS1-2189R-B Recombinant Rhesus Macaque KCNS1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque KCNS1-2189R Recombinant Rhesus Macaque KCNS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Saimiri boliviensis boliviensis (Bolivian squirrel monkey) RFL11353SF Recombinant Full Length Saimiri Boliviensis Boliviensis Potassium Voltage-Gated Channel Subfamily S Member 1(Kcns1) Protein, His-Tagged E.coli expression system His Full Length (1-529)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KCNS1 Related Articles

KCNS1 involved in several pathways and played different roles in them. We selected most pathways KCNS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

KCNS1 has several biochemical functions, for example, acetylcholine receptor binding, protein phosphatase type 1 regulator activity, ubiquitin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNS1 itself. We selected most functions KCNS1 had, and list some proteins which have the same functions with KCNS1. You can find most of the proteins on our site.

Function Related Protein
acetylcholine receptor bindingDLG4;JAK2;UBXN2A;KCNS1;NRXN1;RIC3;RER1;APP;RAPSN
protein phosphatase type 1 regulator activityPPP1R15A;PHACTR1;WBP11;UBXN2A;PPP1R16A;PHACTR3B;PPP1R8;PPP1R7;PHACTR3A
ubiquitin bindingOTUB1;SPRTN;TRIM32;FAM125A;TRP53INP2;NUP62;TOP2A;FAF1;BCL10

KCNS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNS1.

Langford, DJ; West, C; et al. Variations in Potassium Channel Genes Are Associated With Breast Pain in Women Prior to Breast Cancer Surgery. JOURNAL OF NEUROGENETICS 28:122-135(2014).
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