KDM5B
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Official Full Name
lysine (K)-specific demethylase 5B
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Overview
Lysine-specific demethylase 5B also known as histone demethylase JARID1B is a demethylase enzyme that in humans is encoded by the KDM5B gene. -
Synonyms
CT31; PLU1; PUT1; PLU-1; JARID1B; FLJ10538; FLJ12459; FLJ12491; FLJ16281; FLJ23670; RBBP2H1A; lysine-specific demethylase 5B; RBP2-H1; OTTHUMP00000038815; OTTHUMP00000038816; OTTHUMP00000197658; cancer/testis antigen 31; histone demethylase JARID1B; putative DNA/chromatin binding motif; jumonji, AT rich interactive domain 1B; jumonji/ARID domain-containing protein 1B; retinoblastoma-binding protein 2 homolog 1; retinoblastoma-binding protein 2, homolog 1A; KDM5B; lysine (K)-specific demethylase 5B;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- Mammalian Cell
- Sf9 Insect Cell
- Flag
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | KDM5B-44H | Active Recombinant Human KDM5B, FLAG-tagged | Sf9 Insect Cell | Flag |
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| Human | KDM5B-752H | Recombinant Human KDM5B | Mammalian Cell | His |
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| Human | KDM5B-4992HCL | Recombinant Human KDM5B 293 Cell Lysate | HEK293 | N/A |
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| Human | KDM5B-3798H | Recombinant Human KDM5B protein, His-tagged | E.coli | His | 190-309 aa | |
| Human | KDM5B-301312H | Recombinant Human KDM5B protein, GST-tagged | E.coli | GST | Ser190-Leu309 |
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| Human | KDM5B-3200H-B | Recombinant Human KDM5B Protein Pre-coupled Magnetic Beads | HEK293 |
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| Human | KDM5B-3200H | Recombinant Human KDM5B Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | Kdm5b-261M | Recombinant Mouse Kdm5b, GST-tagged | Sf9 Insect Cell | GST |
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| Mouse | KDM5B-8595M | Recombinant Mouse KDM5B Protein | Mammalian Cell | His |
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| Mouse | KDM5B-4783M | Recombinant Mouse KDM5B Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | KDM5B-4783M-B | Recombinant Mouse KDM5B Protein Pre-coupled Magnetic Beads | HEK293 |
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| Chicken | KDM5B-2709C | Recombinant Chicken KDM5B | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- KDM5B Related Research Area
KDM5B involved in several pathways and played different roles in them. We selected most pathways KDM5B participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HDMs demethylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with KDM5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin modifying enzymes | KDM7AB;PBRM1;DMAP1;MBD3;SAP130;ELP4;KDM2A;ZZZ3;SMYD2A |
| Chromatin organization | TADA3;C17orf81;KAT6B;ZZZ3;KDM6AL;KDM5BA;GATAD2AB;ACTL6B;C3orf75 |
| HDMs demethylate histones | KDM4D;KDM2A;KDM5A;KDM6B;KDM6AL;KDM4A;KDM5BA;KDM1A;PHF8 |
KDM5B has several biochemical functions, for example, DNA binding, histone demethylase activity (H3-K4 specific), histone demethylase activity (H3-dimethyl-K4 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by KDM5B itself. We selected most functions KDM5B had, and list some proteins which have the same functions with KDM5B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | KLF8;HMGB1B;TAF6L;SPO11;SATB1A;POU2AF1;HIST1H111L;ZNF398;PROX1 |
| histone demethylase activity (H3-K4 specific) | KDM5D;C14orf169;KDM5B;KDM1A;KDM5C |
| histone demethylase activity (H3-dimethyl-K4 specific) | KDM5B;KDM5BB;KDM1B;KDM1A |
| histone demethylase activity (H3-trimethyl-K4 specific) | KDM5BB;KDM5B |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | EGLN2;JHDM1D;ALKBH4;KDM5C;ALKBH8;ALKBH5;EGLN1;EGLN3;KDM5BB |
| protein binding | CRBN;PRL;DRD1;VEPH1;DOCK4;SLC25A18;GNPDA1;HHLA2;PDS5A |
| transcription corepressor activity | BASP1;C1QBP;E2F7;BHLHE40;ZBTB32;CITED2;LIMD1;ID4;HIRA |
| transcription factor activity, sequence-specific DNA binding | HES6;VDRB;MYCS;KLF4;RFXANK;GTF2H3;ZKSCAN5;PBX1A;PFDN1 |
| zinc ion binding | TRIM41;AMFR;L3MBTL4;XRN2;LONRF1L;RARAA;MMP25;MT1;SOD3A |
KDM5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KDM5B here. Most of them are supplied by our site. Hope this information will be useful for your research of KDM5B.
CTCF; PPP1CA; PRPF4; brca1_human_gene; CDC14A; TGFB2; ESRP1; CAV1; PALD1; ctgf_human_gene; CHST3; PTGIS
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