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KERA

  • Official Full Name

    keratocan

  • Overview

    The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).
  • Synonyms

    KERA; keratocan; CNA2; keratocan proteoglycan; SLRR2B; KERA_HUMAN; Keratan sulfate proteoglycan keratocan; KTN;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Others
  • Cattle
  • Chicken
  • Goat
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • Goat cornea
  • HEK293
  • Mammalian Cell
  • His
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KERA-4989HCL Recombinant Human KERA 293 Cell Lysate HEK293 N/A
Human KERA-2359H Recombinant Human KERA Protein, His-tagged E.coli N-His His38-Pro335
Mouse Kera-7880M Recombinant Mouse Kera protein, His & T7-tagged E.coli His/T7 Gln21~His292 (Accession # O35367)
Cattle KERA-7879C Recombinant Cattle KERA protein, His & T7-tagged E.coli His/T7 Arg21~Asn292 (Accession # O62702)
Goat KERA-01G Active Native Goat KERA protein Goat cornea 352aa
Zebrafish KERA-3161Z Recombinant Zebrafish KERA Mammalian Cell His
Chicken KERA-5750C Recombinant Chicken KERA Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KERA Related Articles

KERA involved in several pathways and played different roles in them. We selected most pathways KERA participated on our site, such as Defective B4GALT1 causes B4GALT1-CDG (CDG-2d), Defective CHST6 causes MCDC1, Defective ST3GAL3 causes MCT12 and EIEE15, which may be useful for your reference. Also, other proteins which involved in the same pathway with KERA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)OGN;PRELP;KERA;ACAN;FMOD
Defective CHST6 causes MCDC1KERA;ACAN;OGN;FMOD;PRELP
Defective ST3GAL3 causes MCT12 and EIEE15PRELP;ACAN;OGN;KERA;FMOD
DiseaseFDXR;CFTR;OGN;AP2B1;CTDP1;HDAC6;SSRP1;CDC37;KPNA5
Diseases associated with glycosaminoglycan metabolismACAN;KERA;PRELP;FMOD;OGN
Diseases of glycosylationACAN;FMOD;KERA;PRELP;OGN
Glycosaminoglycan metabolismSLC26A2;CHST14;SLC35D2;STAB2;GPC5A;DSEL;FMODA;BGNB;B3GNT2
Keratan sulfate biosynthesisB3GNT1;PRELP;B3GNT2A;SLC35D2;B3GNT3;OMD;FMODA;KERA;ST3GAL3A

KERA has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by KERA itself. We selected most functions KERA had, and list some proteins which have the same functions with KERA. You can find most of the proteins on our site.

Function Related Protein
molecular_functionHN1A;LRRC8E;WSCD2;MYADML2;TMEM131;ARL14EPL;GPR62;PPFIBP2;TDPOZ4

KERA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KERA here. Most of them are supplied by our site. Hope this information will be useful for your research of KERA.

Dlg4; CDC37

Conrad, AH; Conrad, GW; et al. The keratocan gene is expressed in both ocular and non-ocular tissues during early chick development. MATRIX BIOLOGY 22:323-337(2003).
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