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KIF2C

Official Full Name

kinesin family member 2C
Overview

The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. [provided by RefSeq, Jul 2008]
Synonyms

KIF2C; kinesin family member 2C; MCAK; CT139; KNSL6; kinesin-like protein KIF2C; kinesin-like 6; kinesin-like protein 6; mitotic centromere-associated kinesin;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	KIF2C-372H	Recombinant Human KIF2C, GST-tagged	E.coli	GST	255-518aa	$319 / 25ug
Human	KIF2C-4946HCL	Recombinant Human KIF2C 293 Cell Lysate	HEK293	N/A		Inquiry
Human	KIF2C-1164H	Recombinant Human KIF2C Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Kif2c-3693M	Recombinant Mouse Kif2c Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	KIF2C-6456Z	Recombinant Zebrafish KIF2C	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
KIF2C Related Gene Family

KIF2C involved in several pathways and played different roles in them. We selected most pathways KIF2C participated on our site, such as Adaptive Immune System, Aurora B signaling, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adaptive Immune System	AGO1;GAN;TRIM11;FGF20A;CTSE;DCTN2;KIF26A;FCGR1B;ASB9
Aurora B signaling	NCAPD2;NSUN2;INCENP;RACGAP1;NDC80;NPM1;SEPT1;AURKC;CDCA8
Cell Cycle	TFDP2;MAD2L2;SMC4;ABL1;KIF2B;TCTN2;MSH5;E2F2;ORC1
Cell Cycle, Mitotic	STAG1;CDKN2B;CENPE;TUBGCP2;MCM8;OFD1;PHF8;CSNK2B;SMC2
Factors involved in megakaryocyte development and platelet production	HBBE1.1;KIF2B;HBB-Y;H3F3D;KIF4A;KIF5B;KIF15;AKAP1B;RACGAP1
Hemostasis	KCNMB2;KIFAP3;CALU;ATP2B3A;CLEC1B;STXBP3A;CFHL4;KIF11;SLC7A8A
Immune System	ARIH1L;KLRB1B;CD200R1;LILRB5;PPAPDC1A;RAPGEF4;DEFB116;CD207;TAX1BP1B
Kinesins	KIF11;KIF26A;KIF2C;KIFC1;KIF3C;KIF18A;KIF15;KIF4;KIF4A

KIF2C has several biochemical functions, for example, ATP binding, ATPase activity, centromeric DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF2C itself. We selected most functions KIF2C had, and list some proteins which have the same functions with KIF2C. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	DGKD;CHORDC1;TOP2B;ASS1;ORC4;VCP;ADCY7;ACTR3;PANK1B
ATPase activity	DYNC2H1;ABCB6;PSMD6;ABCA1B;MYO19;ATAD1A;CLPB;KIF22;ABCF2
centromeric DNA binding	CENPC1;ZW10;MLH3;KIF2C;MSH3;CENPB;MSH2
microtubule motor activity	KIF15;KIF12;DNAH11;BBS4;KIFC3;DNAIC2;DYNC1I1;DYNC1LI1;KIF26A
microtubule plus-end binding	CLIP2;APC;STIM1;MAPRE1;CLIP1;KIF18A;CLASP1A;KIF2C;DST
protein binding	UNC119B;PTPRE;LMO3;TAP2;PPHLN1;BIRC7;C11orf46;KIAA1530;MYLK2

KIF2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF2C here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF2C.

MAPRE1; MTUS2; VHL; CSNK2B; ZNF566; KIF2A; KIF2A; SRGAP3; WDR62; CENPB; RPL7; VCAM1