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KLC2

  • Official Full Name

    kinesin light chain 2

  • Overview

    Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules.;Kinesin consists of 2 light chains, such as KLC2, and 2 heavy chains (see KIF5B; MIM 602809) in a 1:1 stoichiometric;ratio (Rahman et al., 1998 (PubMed 9624122)).
  • Synonyms

    KLC2; kinesin light chain 2; FLJ12387; KLC 2; KLC2_HUMAN; OTTHUMP00000165216; OTTHUMP00000165218; OTTHUMP00000165219; OTTHUMP00000165220;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KLC2-625H Recombinant Human KLC2 Protein, GST-tagged Insect Cell GST
Human KLC2-391H Recombinant Human KLC2, GST-tagged E.coli GST 1-355aa
Human KLC2-4934HCL Recombinant Human KLC2 293 Cell Lysate HEK293 N/A
Human KLC2-1945HFL Recombinant Full Length Human KLC2 Protein, C-Flag-tagged Mammalian cells Flag
Human KLC2-5632H Recombinant Human KLC2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human KLC2-1249H-B Recombinant Human KLC2 Protein Pre-coupled Magnetic Beads HEK293
Human KLC2-765H Recombinant Human KLC2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human KLC2-1315H Recombinant Human KLC2 protein(Met1-Gly622), His&GST-tagged Insect Cells N-His&GST Met1-Gly622
Human KLC2-1249H Recombinant Human KLC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Klc2-1274M Recombinant Mouse Klc2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rhesus Macaque KLC2-2410R Recombinant Rhesus monkey KLC2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque KLC2-2231R-B Recombinant Rhesus Macaque KLC2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque KLC2-2231R Recombinant Rhesus Macaque KLC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish KLC2-5408Z Recombinant Zebrafish KLC2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KLC2 Related Articles

KLC2 involved in several pathways and played different roles in them. We selected most pathways KLC2 participated on our site, such as Salmonella infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Salmonella infectionFOS;KLC4;CCL4L2;RHOGB;MAPK11;TLR4BB;MAPK8A;DYNC1I1;ARPC5A

KLC2 has several biochemical functions, for example, kinesin binding, microtubule motor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLC2 itself. We selected most functions KLC2 had, and list some proteins which have the same functions with KLC2. You can find most of the proteins on our site.

Function Related Protein
kinesin bindingJAKMIP1;PLEKHM2;PRC1;KIAA1279;ARHGEF10;ARPC2;NEFH;KIF1B;NEK6
microtubule motor activityKIF15;KLC3;KIF26A;KIFC1;DYNC1LI2;KIF20A;DNHD1;KLC1B;KIF3CB
protein bindingZNF502;KIF2C;CIB4;MARK4;PTRF;ZNF747;TACSTD2;ZNF664-FAM101A;GOLGA2

KLC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLC2.

YWHAQ; YWHAG; YWHAZ; Hap1; SFN; S100A8; COIL; AIMP2; vgrG7; PIK3R3; Cep152; pi3p; KLC1; AP3D1; SOD1

Trejo, HE; Lecuona, E; et al. Role of kinesin light chain-2 of kinesin-1 in the traffic of Na,K-ATPase-containing vesicles in alveolar epithelial cells. FASEB JOURNAL 24:374-382(2010).
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