KLF1
-
Official Full Name
Kruppel-like factor 1 (erythroid)
-
Overview
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. -
Synonyms
KLF1; Kruppel-like factor 1 (erythroid); Krueppel-like factor 1; EKLF; erythroid Kruppel like factor; monoclonal A3D8; erythroid Kruppel-like factor; erythroid krueppel-like transcription factor; erythroid-specific transcription factor EKLF; INLU; HBFQT;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- B2M
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | KLF1-394H | Recombinant Human KLF1, GST-tagged | E.coli | GST | 1-362aa | |
Human | KLF1-395H | Recombinant Human KLF1 protein, His-B2M-tagged | E. coli | His-B2M | 1-362aa | |
Human | KLF1-01H | Recombinant Human KLF1 Protein, His-tagged | E.coli | His | ||
Rhesus Macaque | KLF1-2411R | Recombinant Rhesus monkey KLF1 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | KLF1-2232R | Recombinant Rhesus Macaque KLF1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | KLF1-2232R-B | Recombinant Rhesus Macaque KLF1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | KLF1-8577Z | Recombinant Zebrafish KLF1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
KLF1 involved in several pathways and played different roles in them. We selected most pathways KLF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|
KLF1 has several biochemical functions, for example, core promoter proximal region sequence-specific DNA binding, metal ion binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLF1 itself. We selected most functions KLF1 had, and list some proteins which have the same functions with KLF1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
core promoter proximal region sequence-specific DNA binding | DMRT1;TFAP2A;DMRTC2;DMRT3A;SMAD4;SMAD3;CREBBP;SP3;DMRT3 |
metal ion binding | DPYD;INO80B;CTDSP2;GCM2;PPP1CA;DNMT3L;ADK;ZNF43;ZIK1 |
transcription factor activity, sequence-specific DNA binding | SCMH1;ZNF238;FOXD3;MYRFL;TBX22;SCML1;INSM1A;ZFP161;ZNF573 |
transcription regulatory region DNA binding | GLI1;SMAD7;TBL1X;TCF7L1A;SP1;SALL1A;HOXA13;TOMM20A;IKZF1 |
KLF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLF1.
UBC
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All KLF1 Products
Required fields are marked with *
My Review for All KLF1 Products
Required fields are marked with *