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KLHL20

  • Official Full Name

    kelch-like 20 (Drosophila)

  • Overview

    The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 44-56 amino acid repeat motif. The kelch motif appears in many different polypeptide contexts and contains multiple potential protein-protein contact sites. Members of this family are present both throughout the cell and extracellularly, with diverse activities.
  • Synonyms

    KLHL20; kelch-like 20 (Drosophila); kelch-like protein 20; KHLHX; KLEIP; Kelch like ECT2 interacting protein; Kelch like protein 20; Kelch like protein X; Kelch motif containing protein; Kelch-like ECT2-interacting protein; Kelch-like protein X; KLH20_HUMAN; KLHLX; RP3-383J4.3; kelch-like ECT2 interacting protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • C
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KLHL20-417H Recombinant Human KLHL20, His-tagged E.coli His 261-609aa
Human KLHL20-943HCL Recombinant Human KLHL20 cell lysate N/A
Human KLHL20-418H Recombinant Human KLHL20 protein, His-tagged E.coli C-His 191-340 aa
Mouse KLHL20-8711M Recombinant Mouse KLHL20 Protein Mammalian Cell His
Mouse KLHL20-4855M Recombinant Mouse KLHL20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse KLHL20-4855M-B Recombinant Mouse KLHL20 Protein Pre-coupled Magnetic Beads HEK293
Rat KLHL20-3280R Recombinant Rat KLHL20 Protein Mammalian Cell His
Rat KLHL20-2936R Recombinant Rat KLHL20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KLHL20-2936R-B Recombinant Rat KLHL20 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish KLHL20-12245Z Recombinant Zebrafish KLHL20 Mammalian Cell His
Chicken KLHL20-2983C Recombinant Chicken KLHL20 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KLHL20 Related Articles

KLHL20 involved in several pathways and played different roles in them. We selected most pathways KLHL20 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLHL20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemUBA5;NRG4;LILRB4;KLRB1F;RNF138;SPSB1;CLEC2D;AP1M2;CD300LD
Antigen processing: Ubiquitination &ampASB18;SH3RF1;RNF4;FBXO3;SPSB4;HECTD3;UBE2U;DZIP3;DTX3L
Proteasome degradationUBE2L6;ASB2;SPSB2;DTX3L;ASB17;ASB8;RNF138;TRIM69;RBCK1
Class I MHC mediated antigen processing &ampRNF182;KLHL21;TRIM41;WSB1;VPRBP;MKRN1;ASB13;UBE2F;FBXO27
presentationTRIM41;UBE2V1;FCGR1B;DZIP3;HUWE1;RNF19B;RNF123;TRIM9;SPSB1
E-cadherin signaling in the nascent adherens junctionCTNND1;WASF2;ABI1;NCKAP1;KLHL20
Immune SystemPOLR3F;CASP2;BST2;TRIM62;DYNC1I2;ASB10;TAX1BP1;KPNA5;UBR1

KLHL20 has several biochemical functions, for example, actin binding, interferon-gamma binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLHL20 itself. We selected most functions KLHL20 had, and list some proteins which have the same functions with KLHL20. You can find most of the proteins on our site.

Function Related Protein
actin bindingKLHL3;VPS18;CALD1B;MAEA;CAMK2B;ACE;CORO1A;DIXDC1;DAG1
interferon-gamma binding
protein bindingZNF426;FAF2;TRPC7;PREP;PKMYT1;RANGAP1;XPO7;CCNL2;SESTD1
ubiquitin-protein transferase activityUBE2Q2;HUWE1;UBE2R2;TRIM24;ZNRF3;HECTD3;RFWD3;ZNF738;UBE2G2
contributes_to ubiquitin-protein transferase activityKEAP1B;KLHL38;KLHL21;KLHL32;KLHL24;UBE2S;KBTBD8;BCOR;DDB2

KLHL20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLHL20 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLHL20.

PML; DAPK1

Kather, JN; Friedrich, J; et al. Angiopoietin-1 Is Regulated by miR-204 and Contributes to Corneal Neovascularization in KLEIP-Deficient Mice. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:4295-4303(2014).
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