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KLHL4

Official Full Name

kelch-like 4 (Drosophila)
Overview

This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Synonyms

KLHL4; kelch-like 4 (Drosophila); kelch (Drosophila) like 4; kelch-like protein 4; DKELCHL; KHL4; KIAA1687; KLHL4_HUMAN; OTTHUMP00000023632; OTTHUMP00000023633;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	KLHL4-429H	Recombinant Human KLHL4, GST-tagged	E.coli	GST	15-164aa	$319 / 25ug
Human	KLHL4-944HCL	Recombinant Human KLHL4 cell lysate		N/A		Inquiry
Zebrafish	KLHL4-6178Z	Recombinant Zebrafish KLHL4	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
KLHL4 Related Articles

KLHL4 involved in several pathways and played different roles in them. We selected most pathways KLHL4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLHL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

KLHL4 has several biochemical functions, for example, actin binding, molecular_function, contributes_to ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLHL4 itself. We selected most functions KLHL4 had, and list some proteins which have the same functions with KLHL4. You can find most of the proteins on our site.

Function	Related Protein
actin binding	EPB49;EZR;PHACTR4;TWF1A;DIAPH1;KCNMA1;MYHC4;CYFIP1;ABLIM1A
molecular_function	REXO1;MORC1;GM4836;CCDC160;C19orf57;GM13298;PNPLA4;TMEM144A;FAM115E
contributes_to ubiquitin-protein transferase activity	KLHL30;PHOSPHO2-KLHL23;KLHL42;KLHL21;KBTBD6;KLHL3;KLHL7;KLHL32;KLHL10

KLHL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLHL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLHL4.

NUDCD3; NUDCD2

Aromolaran, KA; Benzow, KA; et al. The Kelch-like protein 1 modulates P/Q-type calcium current density. NEUROSCIENCE 145:841-850(2007).