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KLRC1

  • Official Full Name

    killer cell lectin-like receptor subfamily C, member 1

  • Overview

    NKG2A, NKG2C and NKG2E, are isoforms of the NKG2 lectin-like family. In mice, NKG2 subunits associate with CD94 to form heterodimers at the surface of natural killer (NK) cells.The CD94/NKG2 heterodimer is the receptor for a non-classical MHC class I ligand, which is Qa 1 in the mouse. NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells.
  • Synonyms

    KLRC1; killer cell lectin-like receptor subfamily C, member 1; NKG2-A/NKG2-B type II integral membrane protein; NKG2A; NKG2B; CD159a;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Cynomolgus/Rhesus
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Fc
  • Fc|His
  • GST
  • hFc
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KLRC1-437H Recombinant Human KLRC1, GST-tagged E.coli GST 1-215aa
Human KLRC1-7372H Recombinant Human KLRC1, His tagged E.coli His
Human KLRC1-298H Recombinant Human KLRC1 protein, hFc-tagged HEK293 hFc Pro94-Leu233
Human KLRC1-4917H Recombinant Human KLRC1 Protein Wheat Germ N/A
Human KLRC1-4916H Recombinant Human KLRC1 Protein, GST-tagged Wheat Germ GST
Human KLRC1-593HB Recombinant Human KLRC1 protein, His-tagged, Biotinylated HEK293 His
Human KLRC1-416HB Recombinant Human KLRC1 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi It contains Arg100- Leu233.
Human KLRC1-5898HF Recombinant Full Length Human KLRC1 Protein, GST-tagged In Vitro Cell Free System GST 233 amino acids
Human KLRC1-593H Recombinant Human KLRC1 protein, His-tagged HEK293 His Pro94-Leu233
Human KLRC1-772H Recombinant Human KLRC1 protein, His-Avi-tagged HEK293 His-Avi It contains Arg100- Leu233.
Human KLRC1-5897HF Recombinant Full Length Human KLRC1 Protein In Vitro Cell Free System amino acids
Human KLRC1-088H Recombinant Human KLRC1 Protein, C-His-tagged E.coli C-His
Human KLRC1-4361H Recombinant Human KLRC1 Protein (Arg100-Leu233), N-His tagged Mammalian cells N-His Arg100-Leu233
Human KLRC1-4362H Recombinant Human KLRC1 Protein (Pro94-Leu233), N-Fc tagged Mammalian cells N-Fc Pro94-Leu233
Human KLRC1-192H Recombinant Human KLRC1 and CD94 Protein, Arg100-Leu233 and Ser34-Ile179, N-His-Avi tagged, Biotinylated HEK293 N-His-Avi Arg100-Leu233 (NKG2A) and Ser34-Ile179 (CD94)
Mouse Klrc1-221M Recombinant Mouse Klrc1 protein, Fc-tagged HEK293 Fc
Mouse Klrc1-256M Recombinant Mouse Klrc1, His tagged Human Cell His
Mouse KLRC1-924MCL Recombinant Mouse KLRC1 cell lysate Human Cell N/A
Cynomolgus Monkey KLRC1-110C Recombinant Cynomolgus KLRC1, Fc tagged Human Cell Fc/His
Cynomolgus Monkey KLRC1-644C Recombinant Cynomolgus KLRC1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey KLRC1-986CCL Recombinant Cynomolgus KLRC1 cell lysate Human Cell N/A
Cynomolgus Monkey KLRC1-390C Recombinant Cynomolgus Monkey KLRC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey KLRC1-390C-B Recombinant Cynomolgus Monkey KLRC1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus/Rhesus KLRC1-2217C Recombinant Cynomolgus/Rhesus KLRC1 protein, hFc-tagged HEK293 hFc Pro94-Leu233
Homo sapiens (Human) RFL17484HF Recombinant Full Length Human Nkg2-A/Nkg2-B Type Ii Integral Membrane Protein(Klrc1) Protein, His-Tagged E.coli expression system His Full Length (1-233)
Rhesus Macaque KLRC1-2435R Recombinant Rhesus monkey KLRC1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque KLRC1-2256R Recombinant Rhesus Macaque KLRC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque KLRC1-2256R-B Recombinant Rhesus Macaque KLRC1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KLRC1 Related Research Area

KLRC1 involved in several pathways and played different roles in them. We selected most pathways KLRC1 participated on our site, such as Antigen processing and presentation, Natural killer cell mediated cytotoxicity, Graft-versus-host disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Antigen processing and presentationRFX5;RFXANK;HSPA8;HLA-DRB4;KIR3DL2;HLA-DQB1;KIR2DL3;IFI30;HSPA4
Natural killer cell mediated cytotoxicityIFNA13;KIR3DL2;IFNA16;GM-CSF;KIR2DS2;PRKCB;ITGB2;PRKCA;HLA-C
Graft-versus-host diseaseHLA-DPA1;Fasl;H2-Q10;HLA-DQB1;HLA-DRA;FAS;HLA-A;HLA-B;Il2

KLRC1 has several biochemical functions, for example, MHC class I protein complex binding, carbohydrate binding, NOT protein antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLRC1 itself. We selected most functions KLRC1 had, and list some proteins which have the same functions with KLRC1. You can find most of the proteins on our site.

Function Related Protein
MHC class I protein complex bindingKLRD1;KLRC2;KLRC1
carbohydrate bindingPKD1L2;SELL;CNTN2;LGALS3;CLEC18B;GALNT11;GALNT13;KLRK1;ASGR2
NOT protein antigen binding
protein bindingNEFL;FABP1;AKTIP;SRA1;ERBB2;PLEC;KHDC1A;FBXL15;VPS53
transmembrane signaling receptor activityLILRB5;TNFRSF10C;LGR5;LEPR;KLRC2;FZD1;GPR133;TLR10;CLDN3

KLRC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRC1.

MAL; PMP22

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