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KLRF1

  • Official Full Name

    killer cell lectin-like receptor subfamily F, member 1

  • Overview

    KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK);cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 (PubMed 18922855)).
  • Synonyms

    KLRF1; killer cell lectin-like receptor subfamily F, member 1; killer cell lectin-like receptor subfamily F member 1; CLEC5C; NKp80; Activating coreceptor NKp80; C type lectin domain family 5 member C; killer cell lectin like receptor F1; Killer cell lectin like receptor subfamily F member 1; KLRF 1; Lectin like receptor F1; MGC119907; MGC119908; MGC119909; ML; OTTHUMP00000238675; OTTHUMP00000238676; OTTHUMP00000238678; lectin-like receptor F1; killer cell lectin-like receptor F1; C-type lectin domain family 5 member C;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • Rhesus Macaque
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Fc
  • GST
  • hFc
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KLRF1-5672H Active Recombinant Human Killer Cell Lectin-Like Receptor Subfamily F, Member 1, Fc-tagged Mammalian cells Fc
Human KLRF1-113H Recombinant Human KLRF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human KLRF1-5774HF Recombinant Full Length Human KLRF1 Protein, GST-tagged In Vitro Cell Free System GST 124 amino acids
Human KLRF1-113H-B Recombinant Human KLRF1 Protein Pre-coupled Magnetic Beads HEK293
Human KLRF1-4908H Recombinant Human KLRF1 Protein, GST-tagged Wheat Germ GST
Cynomolgus KLRF1-1545C Active Recombinant Cynomolgus KLRF1 protein, hFc-tagged HEK293 hFc Val66-Tyr231
Cynomolgus Monkey KLRF1-645C Recombinant Cynomolgus KLRF1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey KLRF1-92C Recombinant cynomolgus KLRF1, Fc tagged Human Cell His
Cynomolgus Monkey KLRF1-1034CCL Recombinant Cynomolgus KLRF1 cell lysate Human Cell N/A
Cynomolgus Monkey KLRF1-391C-B Recombinant Cynomolgus Monkey KLRF1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey KLRF1-391C Recombinant Cynomolgus Monkey KLRF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque KLRF1-2439R Recombinant Rhesus monkey KLRF1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque KLRF1-2260R Recombinant Rhesus Macaque KLRF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque KLRF1-2260R-B Recombinant Rhesus Macaque KLRF1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KLRF1 Related Research Area

KLRF1 involved in several pathways and played different roles in them. We selected most pathways KLRF1 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemASB8;ARF1;MGC174155;B2ML;RNF34;UBA5;AP2B1;KLRB1F;MICA
Immune SystemOSBPL1A;KIF2C;TRIM39;WASF3;TRIM63;ISG20;RNF25;CMTM2A;RBCK1
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellKLRG1;LILRB1;LILRB2;SLAMF6;KLRF1;GM11711;SIGLEC5;KIR2DS2;CD300LD

KLRF1 has several biochemical functions, for example, MHC class I receptor activity, carbohydrate binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLRF1 itself. We selected most functions KLRF1 had, and list some proteins which have the same functions with KLRF1. You can find most of the proteins on our site.

Function Related Protein
MHC class I receptor activityCD160;KLRF1;KIR3DS1;MR1;LILRB1
carbohydrate bindingOS9;GALNT3;CD209C;GALNT5;SIGLEC9;KLRC2;KLRB1A;C15orf24;POC1BL
transmembrane signaling receptor activityCD27;OR115-6;OR4D2;FZD3B;CLDN4;CD79A;P2RX5;CLEC2D;LYVE1

KLRF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRF1.

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