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LMNB1

  • Official Full Name

    lamin B1

  • Overview

    Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
  • Synonyms

    LMNB1; lamin B1; lamin-B1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LMNB1-29911TH Recombinant Human LMNB1 Wheat Germ N/A 80 amino acids
Human LMNB1-266H Recombinant Human LMNB1 protein, His-tagged E.coli His Ser52~Gly233
Human LMNB1-28298TH Recombinant Human LMNB1 Wheat Germ N/A 586 amino acids
Human LMNB1-260H Recombinant Human LMNB1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human LMNB1-994HCL Recombinant Human LMNB1 cell lysate N/A
Human LMNB1-216H Recombinant Human LMNB1 protein, His-tagged E. coli His 237-587 aa
Human LMNB1-6274HFL Recombinant Full Length Human LMNB1 protein, Flag-tagged Mamanlian cells Flag
Human LMNB1-1305H Recombinant Human LMNB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human LMNB1-301578H Recombinant Human LMNB1 protein, GST-tagged E.coli GST Glu237-Met587
Human LMNB1-1638HFL Recombinant Full Length Human LMNB1 Protein, C-Flag-tagged Mammalian cells Flag
Human LMNB1-2690H Recombinant Human LMNB1 protein(11-420 aa), C-His-tagged E. coli C-His 11-420 aa
Human LMNB1-1305H-B Recombinant Human LMNB1 Protein Pre-coupled Magnetic Beads HEK293
Human LMNB1-285HF Recombinant Full Length Human LMNB1 Protein In Vitro Cell Free System 586 amino acids
Human LMNB1-4449H Recombinant Human LMNB1 Protein (Ala426-Glu558), N-His tagged E.coli N-His Ala426-Glu558
Mouse LMNB1-9154M Recombinant Mouse LMNB1 Protein Mammalian Cell His
Mouse LMNB1-5117M Recombinant Mouse LMNB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Lmnb1-1325M Recombinant Mouse Lmnb1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse LMNB1-5117M-B Recombinant Mouse LMNB1 Protein Pre-coupled Magnetic Beads HEK293
Rat LMNB1-3428R Recombinant Rat LMNB1 Protein Mammalian Cell His
Rat LMNB1-3084R Recombinant Rat LMNB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LMNB1-3084R-B Recombinant Rat LMNB1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque LMNB1-2533R Recombinant Rhesus monkey LMNB1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque LMNB1-2353R Recombinant Rhesus Macaque LMNB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque LMNB1-2353R-B Recombinant Rhesus Macaque LMNB1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish LMNB1-9438Z Recombinant Zebrafish LMNB1 Mammalian Cell His
Chicken LMNB1-6838C Recombinant Chicken LMNB1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LMNB1 Related Articles
  • LMNB1 Related Research Area

LMNB1 involved in several pathways and played different roles in them. We selected most pathways LMNB1 participated on our site, such as Apoptosis, Apoptotic cleavage of cellular proteins, Apoptotic execution phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with LMNB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ApoptosisPPP3CCB;IL3;NGF;SPNA2;DCC;CASP3B;DBNL;Fasl;HIST1H1A
Apoptotic cleavage of cellular proteinsDBNLB;DSG3;DSG1;CASP8L1;STK24;ADD1;CASP6L1;CLSPN;PTBP3
Apoptotic execution phaseHMGB2A;CTNNB2;DBNL;HMGB2;ADD1;PTBP3;CLSPN;SPNA2;BMX
Breakdown of the nuclear laminaLMNB1;CASP6L1;CASP6L2
Caspase cascade in apoptosisPARP1;DFFA;TFAP2A;DIABLO;LMNB1;CRADD;CASP2;CFL2;NUMA1
Cell CycleLIN54;E2F2;SPO11;SKP2;ARPP19;NUDC;TBC1D8;BRCC3;PLK4
Cell Cycle, MitoticCEP290;CETN2;CENPN;CENPQ;NDEL1A;ARPP19B;E2F2;GORASP2;NCAPH2
Cellular SenescenceHTATIP;HMGA1B;RAD50;CEBPB;SUZ12B;SUZ12;HIST3H2BB;CDK6;KAT5

LMNB1 has several biochemical functions, for example, phospholipase binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LMNB1 itself. We selected most functions LMNB1 had, and list some proteins which have the same functions with LMNB1. You can find most of the proteins on our site.

Function Related Protein
phospholipase bindingCALM2;CALM3;PTPN11;LMNB1;CALM;SERPINB1A;SNCA;ARHGAP6;APOC2
structural molecule activityINAA;LELP1;SPRR2F;SEMG1;EPB41L2;KRT32;LAMC3;CLDN7B;CLDN10B

LMNB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LMNB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LMNB1.

LRRK2; PASK; SEPT12; RTCA; AIRE; BCAR3; ATG12; ZWINT; HLA-B; YWHAZ; Atm; PIAS2; SERPINA3; LMNA; ATF4; GIT2; y1085_fratt

Nishida, Y; Aida, K; et al. Antibody-Validated Proteins in Inflamed Islets of Fulminant Type 1 Diabetes Profiled by Laser-Capture Microdissection Followed by Mass Spectrometry. PLOS ONE 9:-(2014).
Liu, H; Zhang, JL; et al. Screening of autoantibodies as potential biomarkers for hepatocellular carcinoma by using T7 phase display system. CANCER EPIDEMIOLOGY 36:82-88(2012).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does LMNB1 impact cell division and replication? 10/16/2021

LMNB1 is involved in regulating nuclear envelope breakdown and reformation during cell division, ensuring accurate replication and segregation of genetic material.

How does LMNB1 relate to aging and age-related diseases? 07/02/2021

Altered LMNB1 function has been associated with cellular aging and age-related diseases, but the exact mechanisms are still under investigation.

How is LMNB1 protein linked to certain genetic disorders? 08/08/2019

Mutations in the LMNB1 gene can lead to genetic disorders like autosomal dominant leukodystrophy (ADLD) and other related conditions.

Can LMNB1 protein be a therapeutic target for genetic disorders? 05/04/2017

Research is ongoing to explore potential therapeutic strategies targeting LMNB1 and associated conditions, but there are no established treatments at this time.

Are there any diagnostic tests available to detect LMNB1 gene mutations? 03/03/2016

Yes, genetic testing can identify mutations in the LMNB1 gene to diagnose conditions like ADLD.

Customer Reviews (3)

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Reviews
11/14/2022

    Its exceptional sensitivity and specificity make it an ideal choice for quantitative protein detection and analysis.

    07/01/2020

      Its versatility and reliability make LMNB1 an excellent option for researchers seeking top-notch performance in ELISA and protein electron microscopy structure analysis.

      12/03/2019

        LMNB1 is extensively used in protein electron microscopy structure analysis due to its compatibility with this technique, providing crucial insights into molecular architectures.

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