LMNB1
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Official Full Name
lamin B1
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Overview
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. -
Synonyms
LMNB1; lamin B1; lamin-B1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mamanlian cells
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- Flag
- GST
- His (Fc)
- Avi
- MYC
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- LMNB1 Related Articles
- LMNB1 Related Research Area
LMNB1 involved in several pathways and played different roles in them. We selected most pathways LMNB1 participated on our site, such as Apoptosis, Apoptotic cleavage of cellular proteins, Apoptotic execution phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with LMNB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Apoptosis | PPP3CCB;IL3;NGF;SPNA2;DCC;CASP3B;DBNL;Fasl;HIST1H1A |
Apoptotic cleavage of cellular proteins | DBNLB;DSG3;DSG1;CASP8L1;STK24;ADD1;CASP6L1;CLSPN;PTBP3 |
Apoptotic execution phase | HMGB2A;CTNNB2;DBNL;HMGB2;ADD1;PTBP3;CLSPN;SPNA2;BMX |
Breakdown of the nuclear lamina | LMNB1;CASP6L1;CASP6L2 |
Caspase cascade in apoptosis | PARP1;DFFA;TFAP2A;DIABLO;LMNB1;CRADD;CASP2;CFL2;NUMA1 |
Cell Cycle | LIN54;E2F2;SPO11;SKP2;ARPP19;NUDC;TBC1D8;BRCC3;PLK4 |
Cell Cycle, Mitotic | CEP290;CETN2;CENPN;CENPQ;NDEL1A;ARPP19B;E2F2;GORASP2;NCAPH2 |
Cellular Senescence | HTATIP;HMGA1B;RAD50;CEBPB;SUZ12B;SUZ12;HIST3H2BB;CDK6;KAT5 |
LMNB1 has several biochemical functions, for example, phospholipase binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LMNB1 itself. We selected most functions LMNB1 had, and list some proteins which have the same functions with LMNB1. You can find most of the proteins on our site.
Function | Related Protein |
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phospholipase binding | CALM2;CALM3;PTPN11;LMNB1;CALM;SERPINB1A;SNCA;ARHGAP6;APOC2 |
structural molecule activity | INAA;LELP1;SPRR2F;SEMG1;EPB41L2;KRT32;LAMC3;CLDN7B;CLDN10B |
LMNB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LMNB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LMNB1.
LRRK2; PASK; SEPT12; RTCA; AIRE; BCAR3; ATG12; ZWINT; HLA-B; YWHAZ; Atm; PIAS2; SERPINA3; LMNA; ATF4; GIT2; y1085_fratt
- Q&As
- Reviews
Q&As (5)
Ask a questionLMNB1 is involved in regulating nuclear envelope breakdown and reformation during cell division, ensuring accurate replication and segregation of genetic material.
Altered LMNB1 function has been associated with cellular aging and age-related diseases, but the exact mechanisms are still under investigation.
Mutations in the LMNB1 gene can lead to genetic disorders like autosomal dominant leukodystrophy (ADLD) and other related conditions.
Research is ongoing to explore potential therapeutic strategies targeting LMNB1 and associated conditions, but there are no established treatments at this time.
Yes, genetic testing can identify mutations in the LMNB1 gene to diagnose conditions like ADLD.
Customer Reviews (3)
Write a reviewIts exceptional sensitivity and specificity make it an ideal choice for quantitative protein detection and analysis.
Its versatility and reliability make LMNB1 an excellent option for researchers seeking top-notch performance in ELISA and protein electron microscopy structure analysis.
LMNB1 is extensively used in protein electron microscopy structure analysis due to its compatibility with this technique, providing crucial insights into molecular architectures.
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