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LMX1B

Official Full Name

LIM homeobox transcription factor 1, beta
Overview

This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1;homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the;normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and;dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively;spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms

LMX1B; LIM homeobox transcription factor 1, beta; NPS1; LIM homeobox transcription factor 1-beta; LMX-1.2; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX1.2; MGC138325; MGC142051;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LMX1B-237H	Recombinant Human LMX1B, His-tagged	E.coli	His	1-395aa	Inquiry
Human	LMX1B-600H	Recombinant Human LMX1B, His-tagged	E.coli	His	1-372aa	$319 / 25ug
Human	LMX1B-383HCL	Recombinant Human LMX1B lysate	HEK293	N/A		Inquiry
Mouse	LMX1B-9165M	Recombinant Mouse LMX1B Protein	Mammalian Cell	His		Inquiry
Mouse	LMX1B-5122M	Recombinant Mouse LMX1B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	LMX1B-5122M-B	Recombinant Mouse LMX1B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	LMX1B-6910C	Recombinant Chicken LMX1B	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
LMX1B Related Articles

LMX1B involved in several pathways and played different roles in them. We selected most pathways LMX1B participated on our site, such as SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with LMX1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
SIDS Susceptibility Pathways	MAP2;TSPYL1;TAC1;PHOX2A;MECP2;YBX1;LMX1B;CREM;TPPP

LMX1B has several biochemical functions, for example, protein binding, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LMX1B itself. We selected most functions LMX1B had, and list some proteins which have the same functions with LMX1B. You can find most of the proteins on our site.

Function	Related Protein
protein binding	PTPN11;RPS7;EXOC3;ZC3H15;MDFIC;EPC1;NIPSNAP3A;EIF4A1;FAM124A
sequence-specific DNA binding	GZF1;HOXB8B;NR2F1B;NKX2-8;LHX8;ZNF711;ZNF35;HOXA11A;OTX1B
transcription factor activity, sequence-specific DNA binding	ZNF493;NFYA;NR1D1;AHCTF1;CNOT8;PHF5A;FOXD5;FEV;SCMH1
zinc ion binding	MMP2;UBOX5;TRIM41;CPA1;RC3H1;RNF213;TRIM101;MAN2B1;ESR2

LMX1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LMX1B here. Most of them are supplied by our site. Hope this information will be useful for your research of LMX1B.

CDC37; LDB1

Makarev, E; Gorivodsky, M; et al. Islet1 and Its Co-Factor Ldb1 Are Expressed in Quiescent Cells of Mouse Intestinal Epithelium. PLOS ONE 9:-(2014).

Miller, RL; Knuepfer, MM; et al. FOS-ACTIVATION OF FOXP2 AND LMX1B NEURONS IN THE PARABRACHIAL NUCLEUS EVOKED BY HYPOTENSION AND HYPERTENSION IN CONSCIOUS RATS. NEUROSCIENCE 218:110-125(2012).