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MAGEC2

Official Full Name

melanoma antigen family C, 2
Overview

This gene is a member of the MAGEC gene family. It is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and the other MAGEC genes are clustered on chromosome Xq26-q27.
Synonyms

MAGEC2; melanoma antigen family C, 2; MAGEE1, melanoma antigen, family E, 1, cancer/testis specific; melanoma-associated antigen C2; cancer/testis antigen 10; CT10; MAGE C2; Cancer testis antigen 10; HCA587; Hepatocellular carcinoma associated antigen 587; Hepatocellular carcinoma-associated antigen 587; MAGC2_HUMAN; MAGE C2 antigen; MAGE E1 antigen; MAGE-C2 antigen; MAGE-E1 antigen; Melanoma associated antigen C2; MGC13377; hepatocellular cancer antigen 587; melanoma antigen, family E, 1, cancer/testis specific; MAGEE1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rhesus Macaque

Source

E. coli
E.coli
HEK293
Insect Cell
Mammalian Cell

Tag

DDK
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MAGEC2-152H	Recombinant Human MAGEC2 protein, His-tagged	E.coli	His		Inquiry
Human	MAGEC2-191H	Recombinant Human MAGEC2 protein, His-tagged	E.coli	His		Inquiry
Human	MAGEC2-4541HCL	Recombinant Human MAGEC2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MAGEC2-174H	Recombinant Human MAGEC2 Protein, DDK-tagged	Insect Cell	DDK		Inquiry
Human	MAGEC2-111H	Recombinant Human MAGEC2 protein, His-tagged	E. coli	His	111-367 aa	Inquiry
Human	MAGEC2-749HFL	Recombinant Full Length Human MAGEC2 Protein, N-His-tagged	E.coli	His		Inquiry
Rhesus Macaque	MAGEC2-2628R	Recombinant Rhesus monkey MAGEC2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	MAGEC2-2448R	Recombinant Rhesus Macaque MAGEC2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	MAGEC2-2448R-B	Recombinant Rhesus Macaque MAGEC2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
MAGEC2 Related Articles

MAGEC2 involved in several pathways and played different roles in them. We selected most pathways MAGEC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

MAGEC2 has several biochemical functions, for example, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEC2 itself. We selected most functions MAGEC2 had, and list some proteins which have the same functions with MAGEC2. You can find most of the proteins on our site.

Function	Related Protein
protein binding	CAPG;THBS1;EPC1;KLC2;DYRK4;CTR9;NME5;CCT3;LETMD1
ubiquitin protein ligase binding	TMEM173;AKTIP;SMAD3;SLC25A5;RNF34;CUL1B;ACTG1;UBE2S;TANK

MAGEC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEC2.

TRIM28; TP53; UBE2H

Chen, YT; Panarelli, NC; et al. Cancer-Testis Antigen Expression in Digestive Tract Carcinomas: Frequent Expression in Esophageal Squamous Cell Carcinoma and Its Precursor Lesions. CANCER IMMUNOLOGY RESEARCH 2:480-486(2014).

Beard, RE; Abate-Daga, D; et al. Gene Expression Profiling using Nanostring Digital RNA Counting to Identify Potential Target Antigens for Melanoma Immunotherapy. CLINICAL CANCER RESEARCH 19:4941-4950(2013).