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MAGI1

Official Full Name

membrane associated guanylate kinase, WW and PDZ domain containing 1
Overview

The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms

MAGI1; membrane associated guanylate kinase, WW and PDZ domain containing 1; BAI1 associated protein 1 , BAIAP1; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; AIP3; BAP1; MAGI 1; TNRC19; WWP3; BAI1-associated protein 1; WW;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Mouse
Rat

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	MAGI1-9461M	Recombinant Mouse MAGI1 Protein	Mammalian Cell	His	Inquiry
Mouse	MAGI1-5301M	Recombinant Mouse MAGI1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	MAGI1-5301M-B	Recombinant Mouse MAGI1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	MAGI1-3541R	Recombinant Rat MAGI1 Protein	Mammalian Cell	His	Inquiry
Rat	MAGI1-3197R	Recombinant Rat MAGI1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	MAGI1-3197R-B	Recombinant Rat MAGI1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

MAGI1 involved in several pathways and played different roles in them. We selected most pathways MAGI1 participated on our site, such as Rap signaling pathway, Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Rap signaling pathway	LPAR3;ITGA2B;ITGB2L;PLCE1;MAP2K6;MET;CALML5;MAP2K3;MAGI1
Tight junction	OCLNB;MAGI2;MYH7B;MPDZ;ACTG1;TJP2A;MPP5A;PRKCB;RAB13

MAGI1 has several biochemical functions, for example, ATP binding, alpha-actinin binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGI1 itself. We selected most functions MAGI1 had, and list some proteins which have the same functions with MAGI1. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	DDX20;RTCB;SMARCA4;ABCB1A;NAIP1;HSPD1;MAPK4;CDK1;DNAJA4
alpha-actinin binding	KCNN2;ALMS1;MYOT;LRRC10;PKD2L1;ADORA2A;MAGI1;RARA;XIRP2
nucleotide binding	ATP13A3;SEPT9A;HNRNPH1;CELF3A;PCXB;PABPC1B;ADCY1A;RAB11AL;VDAC2
protein binding	EPHB6;AMMECR1;BEND5;CBX4;USH1C;SGOL1;ZP3;PARP9;CCDC106
protein complex scaffold	ARRB2;AKAP6;AKAP13;AXIN1;SLC9A1;WWC1;C9orf142;WWC3;SEPT2

MAGI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGI1.

Net1; E4