MAN1A2
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Official Full Name
mannosidase, alpha, class 1A, member 2
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Overview
Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information. -
Synonyms
MAN1A2; mannosidase, alpha, class 1A, member 2; mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; MAN1B; Alpha 1,2 mannosidase IB; Mannosidase alpha class 1A member 2; Mannosyl oligosaccharide 1,2 alpha mannosidase IB; Processing alpha 1,2 mannosidase IB; alpha1,2-mannosidase; alpha-1,2-mannosidase IB; processing alpha-1,2-mannosidase IB;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mus musculus (Mouse)
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | MAN1A2-720H | Recombinant Human MAN1A2, GST-tagged | E.coli | GST | 292-641aa | |
Human | MAN1A2-1050HCL | Recombinant Human MAN1A2 cell lysate | N/A | |||
Human | MAN1A2-477H | Recombinant Human MAN1A2 Protein, His-tagged | HEK293 | His | Pro58-Arg641 | |
Homo sapiens (Human) | RFL26323HF | Recombinant Full Length Human Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase Ib(Man1A2) Protein, His-Tagged | E.coli expression system | His | Full Length (1-641) | |
Mus musculus (Mouse) | RFL258MF | Recombinant Full Length Mouse Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase Ib(Man1A2) Protein, His-Tagged | E.coli expression system | His | Full Length (1-641) | |
Rhesus Macaque | MAN1A2-2656R | Recombinant Rhesus monkey MAN1A2 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | MAN1A2-2476R | Recombinant Rhesus Macaque MAN1A2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | MAN1A2-2476R-B | Recombinant Rhesus Macaque MAN1A2 Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
MAN1A2 involved in several pathways and played different roles in them. We selected most pathways MAN1A2 participated on our site, such as Asparagine N-linked glycosylation, Metabolic pathways, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAN1A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Asparagine N-linked glycosylation | TRAPPC10;ALG2;TRAPPC2L;NANP;SERPINA1L;MAN1A2;AREG;MAN1B1;TRAPPC9 |
Metabolic pathways | CELL;COX8A;NDUFB10;HSD17B8;PIPOX;AMY2A3;BCO1L;PTGS2A;TYRP1 |
Metabolism of proteins | KCNA3;DPH2;WDR85;NSFB;SEC22C;LMCD1;DNAJC24;TIMM17A;ADAMTS15 |
N-Glycan biosynthesis | B4GALT1;ST6GAL1;B4GALT2;ZNF408;MGAT4A;ALG10;ALG6;MAN2A1;ALG10B |
N-glycan trimming and elongation in the cis-Golgi | |
Post-translational protein modification | ANKRD28;ADAMTSL5;OTOP2;ADAMTS3;EIF5A;TRAPPC2;ALG2;PREB;ADAMTS8 |
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 | |
Protein processing in endoplasmic reticulum | VIMP;UBE2E1;EDEM2;XBP1;ATXN3L;HSPA2;SEC31A;MAP2K7;PKZ |
MAN1A2 has several biochemical functions, for example, calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAN1A2 itself. We selected most functions MAN1A2 had, and list some proteins which have the same functions with MAN1A2. You can find most of the proteins on our site.
Function | Related Protein |
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calcium ion binding | CALML4A;NKD2A;CASQ1B;CDH9;LTBP2;LETM1;DSG2;CIB1;PCDHB1 |
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | MAN1A2;EDEM1;EDEM2;MAN1C1;MAN1A1;MAN1A;MAN1B1 |
MAN1A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAN1A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAN1A2.
FOS; SP1; GTF2F2; SMAD9
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