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MAN1B1

  • Official Full Name

    mannosidase, alpha, class 1B, member 1

  • Overview

    Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase is an enzyme that in humans is encoded by the MAN1B1 gene.
  • Synonyms

    MAN1B1; mannosidase, alpha, class 1B, member 1; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; alpha 1; 2 mannosidase; endoplasmic reticulum alpha mannosidase 1; endoplasmic reticulum mannosyl oligosaccharide 1; 2 alpha mannosidase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MAN1B1-135H Recombinant Human MAN1B1, His-tagged HEK293 His
Human MAN1B1-4526HCL Recombinant Human MAN1B1 293 Cell Lysate HEK293 N/A
Human MAN1B1-3972H Recombinant Human MAN1B1 Protein (Asp106-Ala699), C-His tagged Mammalian cells C-His Asp106-Ala699
Mouse MAN1B1-9482M Recombinant Mouse MAN1B1 Protein Mammalian Cell His
Mouse MAN1B1-5314M Recombinant Mouse MAN1B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MAN1B1-5314M-B Recombinant Mouse MAN1B1 Protein Pre-coupled Magnetic Beads HEK293
Rat MAN1B1-3550R Recombinant Rat MAN1B1 Protein Mammalian Cell His
Rat MAN1B1-3206R Recombinant Rat MAN1B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MAN1B1-3206R-B Recombinant Rat MAN1B1 Protein Pre-coupled Magnetic Beads HEK293
Mus musculus (Mouse) RFL3249MF Recombinant Full Length Mouse Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase(Man1B1) Protein, His-Tagged E.coli expression system His Full Length (1-658)
Rattus norvegicus (Rat) RFL18306RF Recombinant Full Length Rat Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase(Man1B1) Protein, His-Tagged E.coli expression system His Full Length (1-657)
Zebrafish MAN1B1-5791Z Recombinant Zebrafish MAN1B1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MAN1B1 Related Articles

MAN1B1 involved in several pathways and played different roles in them. We selected most pathways MAN1B1 participated on our site, such as Asparagine N-linked glycosylation, Calnexin/calreticulin cycle, ER Quality Control Compartment (ERQC), which may be useful for your reference. Also, other proteins which involved in the same pathway with MAN1B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Asparagine N-linked glycosylationST8SIA3;NAPAB;ALG2;GNE;LMAN2L;NSFB;MAGT1;TRAPPC4;ST6GAL2B
Calnexin/calreticulin cycleOS9;MAN1B1;DERL2
ER Quality Control Compartment (ERQC)OS9;DERL2;MAN1B1
Metabolic pathwaysCKMA;ENPP3;UGP2A;SLC27A5;B3GNT6;NDUFS4;TPH1A;CBSA;TPO
Metabolism of proteinsADAMTS5;SPCS3;SERPINA7;DMBT1;TIMM21;CTSG;TOMM40;IGFBP2A;TBCD
N-Glycan biosynthesisST6GAL1;ALG12;ALG10B;B4GALT1;DAD1;MAN1A1;MGAT3A;FUT8A;MGAT4A
N-glycan trimming in the ER and Calnexin/Calreticulin cycleMLEC;MAN1B1
Post-translational protein modificationMCFD2;ARSF;ADAMTS10;CNIH2;ALG10B;ARSI;TMED2;NSMCE1;ARSD

MAN1B1 has several biochemical functions, for example, calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAN1B1 itself. We selected most functions MAN1B1 had, and list some proteins which have the same functions with MAN1B1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingPVALB4;AIF1L;MMP12;SCGN;SPARCL1;KCNIP3B;MYLZ3;CIB3;DLK2
mannosyl-oligosaccharide 1,2-alpha-mannosidase activityMAN1C1;EDEM2;EDEM1;MAN1A;MAN1A1;MAN1B1;MAN1A2

MAN1B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAN1B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAN1B1.

DNM2; N; Uso1

Peanne, R; Rymen, D; et al. MAN1B1-CDG: how stressed-out can the Golgi be?. GLYCOBIOLOGY 24:1105-1105(2014).
Haga, Y; et al. ER or Golgi?: Localization of ER Alpha 1,2-Mannosidase I. TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 26:103-105(2014).
  • Q&As
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