Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

MAOB

  • Official Full Name

    monoamine oxidase B

  • Overview

    The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the;mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an;important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral;tissues. This protein preferentially degrades benzylamine and phenylethylamine.
  • Synonyms

    MAOB; monoamine oxidase B; amine oxidase [flavin-containing] B; MAO-B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; monoamine oxidase type B; MGC26382;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Cavia porcellus (Guinea pig)
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • Baculovirus-Insect cells
  • E.coli
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • Human
  • Insect Cell
  • Insect cells
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MAOB-108H Active Recombinant Human MAOB N/A
Human MAOB-109H Active Recombinant Human MAOB Protein Insect cells
Human MAOA-708H Recombinant Human Monoamine Oxidase A Insect Cell N/A
Human MAOB-447H Recombinant Human MAOB Mammalian Cell His
Human MAOB-707H Recombinant Human Monoamine Oxidase B Insect Cell N/A
Human MAOB-27720TH Recombinant Human MAOB, His-tagged E.coli His
Human MAOB-1369H Recombinant Human Monoamine Oxidase B Human N/A
Human MAOB-8316H Recombinant Human MAOB, His tagged E.coli His
Human MAOB-107H Recombinant Human monoamine oxidase B,His-tagged E.coli His
Human MAOB-4516HCL Recombinant Human MAOB 293 Cell Lysate HEK293 N/A
Human MAOB-3427H Recombinant Human MAOB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human MAOB-681H Active Recombinant Human MAOB protein, His-tagged Baculovirus-Insect cells His Ser 2 - Val 520
Human MAOB-3427H-B Recombinant Human MAOB Protein Pre-coupled Magnetic Beads HEK293
Mouse Maob-7976M Recombinant Mouse Maob protein, His & T7-tagged E.coli His/T7 Gln206~Thr505 (Accession # Q8BW75)
Rat Maob-3420R Recombinant Rat Maob, His-tagged E.Coli or Yeast His 520
Rat MAOB-3554R Recombinant Rat MAOB Protein Mammalian Cell His
Rat MAOB-3210R Recombinant Rat MAOB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Maob-1757R Recombinant Rat Maob Protein, His-tagged E.coli N-His Gln206-Thr505
Rat MAOB-3210R-B Recombinant Rat MAOB Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL2618BF Recombinant Full Length Bovine Amine Oxidase [Flavin-Containing] B(Maob) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-520)
Cavia porcellus (Guinea pig) RFL7760CF Recombinant Full Length Guinea Pig Amine Oxidase [Flavin-Containing] B(Maob) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-520)
Rattus norvegicus (Rat) RFL32279RF Recombinant Full Length Rat Amine Oxidase [Flavin-Containing] B(Maob) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-520)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MAOB Related Articles

MAOB involved in several pathways and played different roles in them. We selected most pathways MAOB participated on our site, such as Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAOB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycine, serine and threonine metabolismAMT;AOC2;GLYCTK;BHMT;SDS;AGXT2;GCSHB;AGXT;GNMT
Arginine and proline metabolismGATM;ALDH2.2;P4HA1A;SRM;CKMA;CKMT2;ALDH18A1;OAT;ARG1
Histidine metabolismALDH9A1A.1;ALDH9A1B;ALDH2;ALDH3A1;ALDH2.1;ALDH3B1;HAL;ALDH3A2;ALDH1A3
Tyrosine metabolismHPDB;AOX3;ALDH3A1;GOT2;TPO;TYR;DCT;MIF;DBH
Phenylalanine metabolismHPDA;AOC2;KEG1;TAT;HPD;MAOA;GM4952;HPDB;AOC3
Tryptophan metabolismCAT;RNF25;ALDH1B1;CYP4F12;ACAT2;MAOB;GCDHA;TPH1B;OGDHL
Drug metabolism - cytochrome PALDH3B1;MGST2;UGT1A4;GSTM6;AOX4;UGT1A6B;UGT1A6;UGT1A7C;GSTT1B
Metabolic pathwaysATP6V0A2B;PHGDH;GOT1;PANK1B;MGAT5;AANAT1;EBP;ASL;ASAH1
Serotonergic synapseBRAF;CYP2D26;PRKACG;CYP2C37;MAOA;HTR2A;PLCB3;GNG3;MAP2K1
Dopaminergic synapsePLCB4;DDC;GNG3;PRKACA;PRKCA;GNB3;GNG5;GNAI1;PPP2R3A
Cocaine addictionDRD2;DRD1;CREB3L1;GRM3;GRIN3A;CREB3;ATF6B;ATF4;SLC18A1
AlcoholismHIST1H4F;HIST1H3E;GNAS;GNG10;H2AFY2;HIST1H2AM;HIST1H2AH;HDAC7;SHC3

MAOB has several biochemical functions, for example, electron carrier activity, flavin adenine dinucleotide binding, primary amine oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAOB itself. We selected most functions MAOB had, and list some proteins which have the same functions with MAOB. You can find most of the proteins on our site.

Function Related Protein
electron carrier activityACAD9;TSTA3;ME2;AOX1;AOX4;DHRS3;UQCR11;AKR1C4;ACADS
flavin adenine dinucleotide bindingLDHD;SDHA;NOX5;PPOX;AOX1;DMGDH;GFER;ACOX1;ACADSB
primary amine oxidase activityAOC1;VCAM1;ABP1;AOC2;MAOA;AOC3;MAOB
protein homodimerization activityHPGD;STC2;MAP3K5;TIMM10;MAP3K10;USF2;MID1;HNF1B;CCDC103

MAOB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAOB here. Most of them are supplied by our site. Hope this information will be useful for your research of MAOB.

Dlg4; kynuramine; deprenyl/selegiline; NFYB; SRPK1

Vitalis, T; Alvarez, C; et al. Developmental expression pattern of monoamine oxidases in sensory organs and neural crest derivatives. JOURNAL OF COMPARATIVE NEUROLOGY 464:392-403(2003).
Bradley, M; Soderhall, C; et al. The Wiskott-Aldrich syndrome gene as a candidate gene for atopic dermatitis. ACTA DERMATO-VENEREOLOGICA 81:340-342(2001).
Cutler, NR; Sramek, JJ; et al. Review of the next generation of Alzheimer's disease therapeutics: Challenges for drug development. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 25:27-57(2001).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
What are the implications of MAOB inhibition in psychiatric and neurodegenerative disorders? 06/17/2023

MAOB inhibition can help manage symptoms in psychiatric and neurodegenerative diseases.

What is the potential of MAOB as a biomarker or therapeutic target in neurology? 09/06/2022

MAOB is a potential biomarker and target for neurological disease treatment.

What is the primary function of MAOB in the brain? 01/02/2022

MAOB breaks down neurotransmitters, crucial for neural signaling.

What is the role of MAOB in dopamine metabolism? 05/02/2021

It plays a key role in degrading dopamine, influencing mood and motor control.

How does MAOB activity affect oxidative stress and neuronal health? 08/19/2018

Elevated MAOB activity may lead to oxidative stress and neuronal damage.

How do genetic variations in the MAOB gene influence its enzymatic activity? 04/03/2018

Genetic variations in MAOB can impact its enzymatic activity and neurotransmitter metabolism.

How does MAOB contribute to neurological disorders? 02/10/2018

MAOB is linked to neurological disorders by affecting neurotransmitter catabolism.

Customer Reviews (3)

Write a review
Reviews
04/14/2020

    Key player in our successful research projects.

    12/21/2018

      Exceeds expectations in accuracy and efficiency.

      04/04/2017

        Top-notch protein analysis, impressed with the service.

        Ask a Question for All MAOB Products

        Required fields are marked with *

        My Review for All MAOB Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends