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MARCH2

  • Official Full Name

    membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase

  • Synonyms

    MARCH2;membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase;28038;ENSG00000099785;RNF172;HSPC240;MARCH-II;19p13.2;E3 ubiquitin-protein ligase MARCH2;E3 ubiquitin-protein ligase MARCH2;RING finger protein 172;membrane-associated RING-CH protein II;membrane-associated RING finger protein 2;EC 6.3.2.-;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Danio rerio (Zebrafish) (Brachydanio rerio)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Xenopus laevis (African clawed frog)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • In vitro E. coli expression system
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MARCH2-745H Recombinant Human 41335, GST-tagged E.coli GST 1-140aa
Human MARCH2-4473HCL Recombinant Human MARCH2 293 Cell Lysate HEK293 N/A
Human MARCH2-4472HCL Recombinant Human MARCH2 293 Cell Lysate HEK293 N/A
Human MARCH2-4474HCL Recombinant Human MARCH2 293 Cell Lysate HEK293 N/A
Human MARCH2-2468H Recombinant Human MARCH2 Full Length Transmembrane protein, His-SUMO-tagged In vitro E. coli expression system His-SUMO 1-246aa
Mouse MARCH2-9555M Recombinant Mouse MARCH2 Protein Mammalian Cell His
Mouse MARCH2-5363M Recombinant Mouse MARCH2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MARCH2-5363M-B Recombinant Mouse MARCH2 Protein Pre-coupled Magnetic Beads HEK293
Rat MARCH2-3584R Recombinant Rat MARCH2 Protein Mammalian Cell His
Rat MARCH2-3240R Recombinant Rat MARCH2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MARCH2-3240R-B Recombinant Rat MARCH2 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL28170BF Recombinant Full Length Bovine E3 Ubiquitin-Protein Ligase March2(41335) Protein, His-Tagged E.coli expression system His Full Length (1-245)
Danio rerio (Zebrafish) (Brachydanio rerio) RFL2635DF Recombinant Full Length Danio Rerio E3 Ubiquitin-Protein Ligase March2(41335) Protein, His-Tagged E.coli expression system His Full Length (1-249)
Homo sapiens (Human) RFL9069HF Recombinant Full Length Human E3 Ubiquitin-Protein Ligase March2(March2) Protein, His-Tagged E.coli expression system His Full Length (1-246aa)
Mus musculus (Mouse) RFL2106MF Recombinant Full Length Mouse E3 Ubiquitin-Protein Ligase March2(41335) Protein, His-Tagged E.coli expression system His Full Length (1-246)
Rattus norvegicus (Rat) RFL16799RF Recombinant Full Length Rat E3 Ubiquitin-Protein Ligase March2(41335) Protein, His-Tagged E.coli expression system His Full Length (1-246)
Xenopus laevis (African clawed frog) RFL15778XF Recombinant Full Length Xenopus Laevis E3 Ubiquitin-Protein Ligase March2(41335) Protein, His-Tagged E.coli expression system His Full Length (1-246)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL18276XF Recombinant Full Length Xenopus Tropicalis E3 Ubiquitin-Protein Ligase March2(41335) Protein, His-Tagged E.coli expression system His Full Length (1-246)
Zebrafish MARCH2-3930Z Recombinant Zebrafish MARCH2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MARCH2 Related Articles

MARCH2 involved in several pathways and played different roles in them. We selected most pathways MARCH2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MARCH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MARCH2 has several biochemical functions, for example, ligase activity, protein binding, ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MARCH2 itself. We selected most functions MARCH2 had, and list some proteins which have the same functions with MARCH2. You can find most of the proteins on our site.

Function Related Protein
ligase activityRING1;ACSM2;TRIM23;MYLIPA;RNF2;SIAH2;RNF31;SHPRH;TRIM37
protein bindingCACNA2D1A;C8orf48;SLA2;BOK;PAX6;ISG15;PSMB10;C1QL1;HSD17B8
ubiquitin-protein transferase activityUBE2D4;FBXO4;UBE2H;BIRC5;MARCH8;AMFR;ARIH1;TRIM37;PEX12
zinc ion bindingSIRT6;DNMT5;AJUBA;SAMHD1;LANCL1;TTF2;ZFAND5A;CXXC1;AGBL5

MARCH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARCH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARCH2.

LDLRAD1; SYNE4; CCDC155; FATE1

Wang, G; Liu, J; et al. MARCH2: Comparative Assessment of Therapeutic Effects of Acarbose and Metformin in Newly Diagnosed Type 2 Diabetes Patients. PLOS ONE 9:-(2014).
Cheng, J; Guggino, W; et al. Ubiquitination and Degradation of CFTR by the E3 Ubiquitin Ligase MARCH2 through Its Association with Adaptor Proteins CAL and STX6. PLOS ONE 8:-(2013).
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