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MARCH8

  • Official Full Name

    membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase

  • Synonyms

    MARCH8;membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase;23356;ENSG00000165406;MIR;c-MIR;RNF178;MARCH-VIII;10q11.21;E3 ubiquitin-protein ligase MARCH8;E3 ubiquitin-protein ligase MARCH8;RING finger protein 178;membrane-associated RING-CH protein VIII;membrane-associated RING finger protein 8;c-mir, cellular modulator of immune recognition;cellular modulator of immune recognition (c-MIR);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Xenopus laevis (African clawed frog)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MARCH8-26832TH Recombinant Human MARCH8 N/A
Human MARCH8-748H Recombinant Human 41341, GST-tagged E.coli GST 1-158aa
Human MARCH8-4467HCL Recombinant Human MARCH8 293 Cell Lysate HEK293 N/A
Human MARCH8-4468HCL Recombinant Human MARCH8 293 Cell Lysate HEK293 N/A
Human MARCH8-4469HCL Recombinant Human MARCH8 293 Cell Lysate HEK293 N/A
Human MARCH8-3221H Recombinant Human MARCH8 protein, His-tagged E.coli His 1-158 aa
Mouse MARCH8-9561M Recombinant Mouse MARCH8 Protein Mammalian Cell His
Mouse MARCH8-5368M Recombinant Mouse MARCH8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MARCH8-5368M-B Recombinant Mouse MARCH8 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL32071BF Recombinant Full Length Bovine E3 Ubiquitin-Protein Ligase March8(41341) Protein, His-Tagged E.coli expression system His Full Length (1-289)
Homo sapiens (Human) RFL10032HF Recombinant Full Length Human E3 Ubiquitin-Protein Ligase March8(41341) Protein, His-Tagged E.coli expression system His Full Length (1-291)
Mus musculus (Mouse) RFL36496MF Recombinant Full Length Mouse E3 Ubiquitin-Protein Ligase March8(41341) Protein, His-Tagged E.coli expression system His Full Length (1-286)
Xenopus laevis (African clawed frog) RFL11909XF Recombinant Full Length Xenopus Laevis E3 Ubiquitin-Protein Ligase March8(41341) Protein, His-Tagged E.coli expression system His Full Length (1-264)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL33341XF Recombinant Full Length Xenopus Tropicalis E3 Ubiquitin-Protein Ligase March8(41341) Protein, His-Tagged E.coli expression system His Full Length (1-264)
Zebrafish MARCH8-6246Z Recombinant Zebrafish MARCH8 Mammalian Cell His
Chicken MARCH8-5479C Recombinant Chicken MARCH8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MARCH8 Related Articles
  • MARCH8 Related Research Area

MARCH8 involved in several pathways and played different roles in them. We selected most pathways MARCH8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MARCH8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MARCH8 has several biochemical functions, for example, MHC class II protein binding, ligase activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MARCH8 itself. We selected most functions MARCH8 had, and list some proteins which have the same functions with MARCH8. You can find most of the proteins on our site.

Function Related Protein
MHC class II protein bindingCD74B;CD74;MARCH8;CD74A;CD4;LAG3;KRT17
ligase activityTTLL13;HERC2;RBBP6;SMURF2;DTX4;UBE2KB;TRAF7;UFL1;SMURF1
ubiquitin protein ligase activityRNF2;PDZRN3;NEURL3;RNF217;PDZD4;UBE2A;C12orf51;TRAIP;ANKIB1
ubiquitin-protein transferase activityARIH1;UBE2G1;BIRC8;RNF4;LRSAM1;FBXL6;HUWE1;TRIM21;TRIM62
zinc ion bindingMICAL2;KDM2B;ADAM8;GM3258;RNF24;SUV39H1A;IRGF4;RFPL3;KNG1

MARCH8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARCH8 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARCH8.

Funakoshi, Y; Chou, MM; et al. TRE17/USP6 regulates ubiquitylation and trafficking of cargo proteins that enter cells by clathrin-independent endocytosis. JOURNAL OF CELL SCIENCE 127:4750-4761(2014).
Kim, MH; Rebbert, ML; et al. Cell Adhesion in Zebrafish Embryos Is Modulated by March8. PLOS ONE 9:-(2014).
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