MARVELD2
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Official Full Name
MARVEL domain containing 2
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Overview
The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
MARVELD2; MARVEL domain containing 2; deafness, autosomal recessive 49 , DFNB49, MARVEL (membrane associating) domain containing 2 , MRVLDC2; MARVEL domain-containing protein 2; FLJ30532; TRIC; tricellulin; DFNB49; MARVD2; MARVEL (membrane associating) domain containing 2; MARVEL domain containing protein 2; MARVELD 2; MRVLDC2; MARVEL (membrane-associating) domain containing 2;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Mammalian cells
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
MARVELD2 involved in several pathways and played different roles in them. We selected most pathways MARVELD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MARVELD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
MARVELD2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MARVELD2 itself. We selected most functions MARVELD2 had, and list some proteins which have the same functions with MARVELD2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PIR;NCOR2;CYCS;DDA1;GAS2L3;CARTPT;ZBTB48;BLOC1S6;FOXL2 |
MARVELD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARVELD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARVELD2.
MCM7
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