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MAST2

Official Full Name

microtubule associated serine/threonine kinase 2
Overview

Microtubule-associated serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MAST2 gene. The protein encoded by this gene controls TRAF6 and NF-kappaB activity.
Synonyms

MAST2; microtubule associated serine/threonine kinase 2; microtubule-associated serine/threonine-protein kinase 2; KIAA0807; MAST205; EC 2.7.11.1 3; FLJ39200; MAST 2; MAST 205; Microtubule associated testis specific serine/threonine protein kinase; MTSSK; OTTHUMP00000009697 2; OTTHUMP00000046616; RP4 533D7.1; RP4-533D7.1 2; OTTHUMP00000009697; RP4-533D7.1;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MAST2-4457HCL	Recombinant Human MAST2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MAST2-1549H	Recombinant Human MAST2 Protein, GST-tagged	Insect Cell	GST		Inquiry
Human	MAST2-1548H	Recombinant Human MAST2 protein, His & GST-tagged	E.coli	His/GST	Phe512~Phe785 (Accession # Q6P0Q8)	Inquiry
Human	MAST2-4132H	Recombinant Human MAST2 Protein (Phe512-Phe785), N-GST tagged	E.coli	N-GST	Phe512-Phe785	Inquiry

Involved Pathway
Protein Function
Interacting Protein
MAST2 Related Articles

MAST2 involved in several pathways and played different roles in them. We selected most pathways MAST2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAST2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

MAST2 has several biochemical functions, for example, ATP binding, magnesium ion binding, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAST2 itself. We selected most functions MAST2 had, and list some proteins which have the same functions with MAST2. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	PPIP5K1;UBE2R2;PKM2;EHD4;PRKACB;PFKFB2;IRAK3;MLH3;MYH11A
magnesium ion binding	RRAGC;PPM1BA;PDXP;DIS3L2;IDH3G;ZAK;SNCA;CIB2;GTPBP10
microtubule binding	MTAP6;TRAF3IP1;KIF16B;VAPB;GOLSYN;KIF15;CNN3;FAM83D;WDR43
phosphatase binding	TSC2;CSRNP2;PPP1R26;SH3YL1;SH3GL1;SH3RF2;MAPK3;TPRN;PPP1R37
protein binding	STIM1;CAPRIN2;KRT1;ACVR1B;CRHBP;FOXM1;TSPAN1;SPEF1;RNF146
protein serine/threonine kinase activity	SNRKB;CDC42BPB;CLK2;HUNK;ATM;CSNK1G1;CDK5;PIK3CA;CSNK1G2A

MAST2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAST2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAST2.

SLC9A3; CDHR2; SLC9A3; HSP90AB1; GCN1L1; TK1; TPM3; TPM2; TPM1; ACTN2; SUMO2; MXRA7; SMN1; ZNF417; TTN

Janku, F; Garrido-Laguna, I; et al. Novel Therapeutic Targets in Non-small Cell Lung Cancer. JOURNAL OF THORACIC ONCOLOGY 6:1601-1612(2011).

Wood-Kaczmar, A; Kraus, M; et al. An alternatively spliced form of glycogen synthase kinase-3 beta is targeted to growing neurites and growth cones. MOLECULAR AND CELLULAR NEUROSCIENCE 42:184-194(2009).