Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

MATK

  • Official Full Name

    megakaryocyte-associated tyrosine kinase

  • Overview

    The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
  • Synonyms

    MATK; megakaryocyte-associated tyrosine kinase; megakaryocyte-associated tyrosine-protein kinase; CHK; Csk homologous kinase; Csk type protein tyrosine kinase; CTK; DKFZp434N1212; hematopoietic consensus tyrosine lacking kinase; HHYLTK; hydroxyaryl protein kinase; HYL; HYL tyrosine kinase; HYLTK; leukocyte carboxyl terminal src kinase relat; EC 2.7.10.2; Leukocyte carboxyl terminal src kinase related; Lsk; Megakaryocyte associated tyrosine kinase; Megakaryocyte associated tyrosine protein kinase; MGC1708; MGC2101; Protein kinase HYL; Tyrosine kinase MATK; Tyrosine protein kinase CTK; Tyrosylprotein kinase; Csk-homologous kinase; hydroxyaryl-protein kinase; tyrosine-protein kinase CTK; Csk-type protein tyrosine kinase; leukocyte carb;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Insect cells
  • Mammalian Cell
  • Sf21
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MATK-103HFL Active Recombinant Full Length Human MATK Protein, C-His-tagged Sf21 His Full Length
Human MATK-5451H Recombinant Human Megakaryocyte-Associated Tyrosine Kinase, His-tagged E.coli His
Human MATK-4451HCL Recombinant Human MATK 293 Cell Lysate HEK293 N/A
Human MATK-4450HCL Recombinant Human MATK 293 Cell Lysate HEK293 N/A
Human MATK-50H Recombinant Human MATK Protein, GST-tagged Insect cells GST
Human MATK-6365H Recombinant Human MATK Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse MATK-9586M Recombinant Mouse MATK Protein Mammalian Cell His
Mouse Matk-3970M Recombinant Mouse Matk Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse MATK-5386M-B Recombinant Mouse MATK Protein Pre-coupled Magnetic Beads HEK293
Mouse Matk-1767M Recombinant Mouse Matk Protein, His&GST-tagged E.coli N-His&GST Val24-Ala237
Mouse MATK-5386M Recombinant Mouse MATK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MATK-3597R Recombinant Rat MATK Protein Mammalian Cell His
Rat Matk-7972R Recombinant Rat Matk protein, His & T7-tagged E.coli His/T7 Mel1~Gln173 (Accession # P41243)
Rat MATK-3253R-B Recombinant Rat MATK Protein Pre-coupled Magnetic Beads HEK293
Rat MATK-3253R Recombinant Rat MATK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MATK involved in several pathways and played different roles in them. We selected most pathways MATK participated on our site, such as Neurotrophin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MATK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neurotrophin signaling pathwaySH2B3;IRAK4;RPS6KA6;CALML5;MAPK9;CALM2;TP53;PDPK1;NFKBIB

MATK has several biochemical functions, for example, ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MATK itself. We selected most functions MATK had, and list some proteins which have the same functions with MATK. You can find most of the proteins on our site.

Function Related Protein
ATP bindingDDX54;ALPK2;NARS;CKMT2;CHD1;SUCLG2;KSR1;PTK6;KDR
non-membrane spanning protein tyrosine kinase activityFER;ZAP70;TNK2B;BAZ1B;JAK2B;ABL2;PTK2AB;JAK1;PTK2BB
protein bindingRUFY3;HEY1;OBFC1;SF3B4;WBP4;ATCAY;MPDZ;GALNT3;CDC45
protein tyrosine kinase activityALK;DYRK4;NTRK2B;TYK2;PTK2AA;MAP2K1;KIAA1804;IGF1RA;JAK1
receptor bindingRCHY1;RASA1;ACOX1;PDGFRB;FYNB;NXPH3;IAPP;TMED1;P2RX4

MATK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MATK here. Most of them are supplied by our site. Hope this information will be useful for your research of MATK.

LRRK2; ERBB2; HSP90AB1; FRS3; PTK2B; MET; AR; LRRK1; CDC37; CACNA1A; EWSR1

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All MATK Products

Required fields are marked with *

My Review for All MATK Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends