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MAU2

Official Full Name

MAU2 sister chromatid cohesion factor
Overview

Scc4 (Mau2) is the metazoan homologue of Scc4 in S. cerevisiae. In yeast, Scc4 binds to Scc2 to form an essential complex that loads cohesion onto chromosomes. Similarly, the Scc4 / Mau2 protein in metazoans plays a significant role in sister chromatid separation and in loading of cohesin onto chromatin. The Scc2-Scc4 complex is tethered to pre-replication complexes through the Cdc7-Drf1 protein kinase DDK.
Synonyms

MAU2; MAU2 sister chromatid cohesion factor; SCC4; MAU2L; mau-2; KIAA0892; MAU2 chromatid cohesion factor homolog; protein MAU-2; sister chromatid cohesion 4; cohesin loading complex subunit SCC4 homolog;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	MAU2-910HCL	Recombinant Human MAU2 cell lysate		N/A	Inquiry
Mouse	MAU2-9592M	Recombinant Mouse MAU2 Protein	Mammalian Cell	His	Inquiry
Mouse	MAU2-5390M-B	Recombinant Mouse MAU2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	MAU2-5390M	Recombinant Mouse MAU2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry

Involved Pathway
Protein Function
Interacting Protein

MAU2 involved in several pathways and played different roles in them. We selected most pathways MAU2 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Cohesin Loading onto Chromatin, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAU2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell Cycle	CLSPN;ATM;CEP135;ARPP19A;SMC3;FKBP6;CENPO;CDC14A;MCM9
Cell Cycle, Mitotic	CDK7;NCAPG2;MCM10;TUBB4B;CNEP1R1;CETN2;AHCTF1;ESCO2;NUMA1
Cohesin Loading onto Chromatin	PDS5B;PDS5A;WAPAL;NIPBLB;STAG2;NIPBLA;STAG1;MAU2;NIPBL
M Phase	BLZF1;NUDC;NUF2;DULLARD;WAPAL;INCENP;KIF2B;SPC24;VRK1
Mitotic Telophase/Cytokinesis	MAU2;NIPBL;NIPBLA;NIPBLB;NUDC

MAU2 has several biochemical functions, for example, protein N-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAU2 itself. We selected most functions MAU2 had, and list some proteins which have the same functions with MAU2. You can find most of the proteins on our site.

Function	Related Protein
protein N-terminus binding	NCOR2;YWHAQ;CSNK2A2;RELA;NCOA1;ERCC6;PEX14;ERCC3;EIF3E
protein binding	AGAP2;HIST1H2BE;PPIE;SOX15;SHARPIN;CRHR2;ITGB5;SEC24D;ACACA

MAU2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAU2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAU2.

CBX5; C21orf59; CBX1; Myh10; NIPBL; SRCAP; DNAJC7