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MC5R

  • Official Full Name

    melanocortin 5 receptor

  • Overview

    This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation.
  • Synonyms

    MC5R; melanocortin 5 receptor; melanocortin receptor 5; OTTHUMP00000162511; melanocortin-5 receptor; MC2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Ovis aries (Sheep)
  • Pan troglodytes (Chimpanzee)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Sus scrofa (Pig)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MC5R-2428H Recombinant Human MC5R Protein, His-tagged E.coli N-His Met1-Gly37+Leu98-Ile114+Tyr180-Val186+Gln266-Phe273
Rat MC5R-3611R Recombinant Rat MC5R Protein Mammalian Cell His
Rat MC5R-3267R Recombinant Rat MC5R Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MC5R-3267R-B Recombinant Rat MC5R Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL17994BF Recombinant Full Length Bovine Melanocortin Receptor 5(Mc5R) Protein, His-Tagged E.coli expression system His Full Length (1-325)
Homo sapiens (Human) RFL22593HF Recombinant Full Length Human Melanocortin Receptor 5(Mc5R) Protein, His-Tagged E.coli expression system His Full Length (1-325)
Mus musculus (Mouse) RFL9744MF Recombinant Full Length Mouse Melanocortin Receptor 5(Mc5R) Protein, His-Tagged E.coli expression system His Full Length (1-325)
Ovis aries (Sheep) RFL23772OF Recombinant Full Length Sheep Melanocortin Receptor 5(Mc5R) Protein, His-Tagged E.coli expression system His Full Length (1-325)
Pan troglodytes (Chimpanzee) RFL1333PF Recombinant Full Length Pan Troglodytes Melanocortin Receptor 5(Mc5R) Protein, His-Tagged E.coli expression system His Full Length (1-325)
Rattus norvegicus (Rat) RFL15917RF Recombinant Full Length Rat Melanocortin Receptor 5(Mc5R) Protein, His-Tagged E.coli expression system His Full Length (1-325)
Rhesus Macaque MC5R-2696R Recombinant Rhesus monkey MC5R Protein, His-tagged Mammalian Cell His
Rhesus Macaque MC5R-2516R Recombinant Rhesus Macaque MC5R Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MC5R-2516R-B Recombinant Rhesus Macaque MC5R Protein Pre-coupled Magnetic Beads HEK293
Sus scrofa (Pig) RFL12939SF Recombinant Full Length Pig Melanocortin Receptor 5(Mc5R) Protein, His-Tagged E.coli expression system His Full Length (1-294)
Chicken MC5R-2696C Recombinant Chicken MC5R Mammalian Cell His
Chicken MC5R-2427C Recombinant Chicken MC5R Protein, His&GST-tagged E.coli N-His&GST Ala60-Arg158
Kit-0894 TR-FRET PPAR delta Coactivator Assay Kit, goat N/A
Kit-1378 MC5R CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MC5R involved in several pathways and played different roles in them. We selected most pathways MC5R participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MC5R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionPARD3;Chrng;CNR1;P2RX6;GABRB2;GRM4;TAAR6;TACR3L;TAAR9

MC5R has several biochemical functions, for example, hormone binding, melanocortin receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MC5R itself. We selected most functions MC5R had, and list some proteins which have the same functions with MC5R. You can find most of the proteins on our site.

Function Related Protein
hormone bindingLRP2;NPR1;GPR30;NPR3;TTR;MC5R;MC1R;MTNR1A;ADIPOR1A
melanocortin receptor activityMC5RB;MC5RA;MC3R;MC4R;MC5R;MC2R;MC1R
protein bindingHSD17B14;ELK1;GTF2I;CCDC137;HSF1;SART3;CHORDC1;CYS1;GPKOW

MC5R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MC5R here. Most of them are supplied by our site. Hope this information will be useful for your research of MC5R.

MRAP; MRAP2

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