Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

MED13

  • Official Full Name

    mediator complex subunit 13

  • Overview

    This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008]
  • Synonyms

    MED13; mediator complex subunit 13; ARC250; THRAP1; DRIP250; HSPC221; TRAP240; mediator of RNA polymerase II transcription subunit 13; thyroid hormone receptor associated protein 1; thyroid hormone receptor-associated protein 1; activator-recruited cofactor 250 kDa component; thyroid hormone receptor-associated protein, 240 kDa subunit; mediator of RNA polymerase II transcription, subunit 13 homolog; vitamin D3 receptor-interacting protein complex component DRIP250; thyroid hormone receptor-associated protein complex 240 kDa component; thyroid hormone receptor-associated protein complex component TRAP240;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse MED13-9684M Recombinant Mouse MED13 Protein Mammalian Cell His
Mouse MED13-5445M Recombinant Mouse MED13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MED13-5445M-B Recombinant Mouse MED13 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MED13 involved in several pathways and played different roles in them. We selected most pathways MED13 participated on our site, such as Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Thyroid hormone signaling pathwayTHRB;ATP1B3;PLCG2;ATP1B1;ACTB;HRAS;PDPK1;RAF1;STAT1

MED13 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity, receptor activity, thyroid hormone receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MED13 itself. We selected most functions MED13 had, and list some proteins which have the same functions with MED13. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II transcription cofactor activityMED13;CNOT2;MED18;MED31;MED30;MED12;MED9;MED22;MED17
receptor activityNLGN3A;GRIA4B;IL10RB;NLGN1;ADIPOR1B;PAQR5;GRIN1B;P2RY1;GFRA2A
thyroid hormone receptor bindingNSD1;GAS2L1;TAF11;ZNHIT3;MED30;THRAP3;NUP62;MED1;MED4
transcription coactivator activityESR2;MTF1;ARID1A;PRPF6;CITED1;PPARGC1A;TDRD3;TFAP2B;KMT2E
transcription cofactor activityZFP865;MED16;ZNF710A;WDR75;MED12;PSMC5;MED13;IRF3;HES6

MED13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED13 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED13.

Tfcp2l1; Tada2a; Kat2a

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All MED13 Products

Required fields are marked with *

My Review for All MED13 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends