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MED16

  • Official Full Name

    mediator complex subunit 16

  • Overview

    Mediator of RNA polymerase II transcription subunit 16 is an enzyme that in humans is encoded by the MED16 gene.
  • Synonyms

    MED16; mediator complex subunit 16; THRAP5, thyroid hormone receptor associated protein 5; mediator of RNA polymerase II transcription subunit 16; DRIP92; TRAP95; DRIP 92; MED 16; THRAP 5; Thyroid hormone receptor associated protein 5; Thyroid hormone receptor associated protein complex 95 kDa component; Trap 95; Vitamin D3 receptor interacting protein complex component; thyroid hormone receptor-associated protein 5; thyroid hormone receptor-associated protein, 95-kD subunit; vitamin D3 receptor-interacting protein complex 92 kDa component; thyroid hormone receptor-assoc; THRAP5;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MED16-31175TH Recombinant Human MED16, His-tagged E.coli His
Human MED16-4477H Recombinant Human MED16 Protein, GST-tagged Wheat Germ GST
Human MED16-6211HF Recombinant Full Length Human MED16 Protein, GST-tagged In Vitro Cell Free System GST 860 amino acids
Zebrafish MED16-7886Z Recombinant Zebrafish MED16 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MED16 involved in several pathways and played different roles in them. We selected most pathways MED16 participated on our site, such as Developmental Biology, Fatty acid, triacylglycerol, and ketone body metabolism, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Developmental BiologyTRPC5;LGI2B;ARPC2;PITPNA;RHOAE;LGI2;POU5F3;EFNB3;WDR83
Fatty acid, triacylglycerol, and ketone body metabolismG0S2;MED10;CPT1B;GPAT2;TIAM2;MED23;ACOT12;ACOT7;CTGF
Gene ExpressionCSTF3;COX4I1;NR2F1;Txn1;LSM10;VDRB;DDOST;METTL3;MTA2
Generic Transcription PathwayZNF582;ZNF620;ZNF189;ZNF136;ZNF394;HELZ2;PRDX2;ZNF692;COX6C
MetabolismFIG4;SLC26A2;MED8;OAZ1A;CDS1;CDO1;CLPS;HELZ2;CD320
Metabolism of lipids and lipoproteinsCEPT1A;AWAT2;CYP2AD3;CHAT;CYP4T8;ALOX5B.3;APOC2;GLTP;MED29
PPARA activates gene expressionMTF1;MED26;MED19;MED23;MED16;GRHL1;SREBF2;G0S2;MED8
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)MED20;MED21;MED19;MED15;MED23;MED9;MED16;MED31;GLIPR1

MED16 has several biochemical functions, for example, catalytic activity, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED16 itself. We selected most functions MED16 had, and list some proteins which have the same functions with MED16. You can find most of the proteins on our site.

Function Related Protein
catalytic activityGOT1L1;ALDOAB;ALPI.1;PCXB;RTCD1;DIP2B;PBLD2;PPM1BA;PPM1E
protein bindingPTK6;NSUN4;RBM11;APLP2;TAF1A;CMKLR1;CYSLTR2;Clec4n;POLR1B
receptor activityATRN;TNFRSF11A;CD200;Siglece;LDLR;SV2A;ANPEP;CADM1A;SLC20A1
thyroid hormone receptor bindingTAF7;MED30;NUP62;MED16;NCOR1;NR0B2;MED4;TAF11;NSD1
thyroid hormone receptor coactivator activityMED16;ACTN2;NCOA2;MED1
transcription coactivator activityPER2;PSMD9;NCOA2;PSMC3;TAF7;SMARCB1;MTA1;HTATIP2;NEUROD1
transcription cofactor activityANKRA2;PIR;LDB2;SND1;ZFP710;TADA2A;MSX2;MAX;MXD1
vitamin D receptor bindingSNW1;MED4;THRAP3;TAF7;MED16;MED14;RXRA;RUNX2B;MED24

MED16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED16 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED16.

MED10; MED19; CDK19; MED26; MED9; MED14; MED24; MED25

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