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MFAP5

  • Official Full Name

    microfibrillar associated protein 5

  • Overview

    This gene encodes a 25-kD microfibril-associated glycoprotein which is rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this encoded protein has some functions that are distinct from those of MFAP2.
  • Synonyms

    MFAP5; microfibrillar associated protein 5; microfibrillar-associated protein 5; MAGP2; MP25; MAGP 2; MAGP-2; MFAP 5; MFAP-5; MFAP5_HUMAN; Microfibril associated glycoprotein 2; Microfibril-associated glycoprotein 2; Microfibrillar associated protein 5 precursor; microfibril-associated glycoprotein-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • CHO
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Fc
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MFAP5-5689H Active Recombinant Human Microfibrillar Associated Protein 5, His-tagged Mammalian cells His
Human MFAP5-8554H Recombinant Human MFAP5, His tagged Human Cell His
Human MFAP5-1395HCL Recombinant Human MFAP5 cell lysate Human Cell N/A
Human MFAP5-4437H Recombinant Human MFAP5 protein, His-SUMO-tagged E.coli His-SUMO 22-173aa
Human MFAP5-290H Recombinant Human MFAP5 Protein, His-tagged E.coli His Leu24~Cys162
Human MFAP5-1243H Recombinant Human MFAP5 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human MFAP5-4387H Recombinant Human MFAP5 Protein, GST-tagged Wheat Germ GST
Human MFAP5-1405H-B Recombinant Human MFAP5 Protein Pre-coupled Magnetic Beads HEK293
Human MFAP5-3683H Recombinant Human MFAP5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MFAP5-1927H Recombinant Human MFAP5 protein, Fc-tagged HEK293 Fc Ile 22 - Leu 173
Human MFAP5-1405H Recombinant Human MFAP5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human MFAP5-5192H Recombinant Human MFAP5 Protein (Leu24-Cys162), His tagged E.coli His Leu24-Cys162
Human MFAP5-6194HF Recombinant Full Length Human MFAP5 Protein, GST-tagged In Vitro Cell Free System GST 173 amino acids
Human MFAP5-853HFL Recombinant Full Length Human MFAP5 Protein, C-Flag-tagged Mammalian cells Flag
Mouse Mfap5-316M Active Recombinant Mouse Mfap5, His-tagged CHO His
Mouse MFAP5-9780M Recombinant Mouse MFAP5 Protein Mammalian Cell His
Mouse MFAP5-5512M Recombinant Mouse MFAP5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Mfap5-291M Recombinant Mouse Mfap5 Protein, His-tagged E.coli His Gly25~Pro152
Mouse MFAP5-5512M-B Recombinant Mouse MFAP5 Protein Pre-coupled Magnetic Beads HEK293
Mouse Mfap5-4055M Recombinant Mouse Mfap5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Mfap5-292R Recombinant Rat Mfap5 Protein, His-tagged E.coli His Asp32~Asp164
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MFAP5 Related Articles
  • MFAP5 Related Research Area
  • MFAP5 Related Signal Pathway

MFAP5 involved in several pathways and played different roles in them. We selected most pathways MFAP5 participated on our site, such as Elastic fibre formation, Extracellular matrix organization, Molecules associated with elastic fibres, which may be useful for your reference. Also, other proteins which involved in the same pathway with MFAP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Elastic fibre formationFBLN2;LOX;LOXL3;LTBP4;FBN2;BMP10;MFAP1;EFEMP1;ABHD1
Extracellular matrix organizationSPARC;COL19A1;COL6A2;TIMP2A;TIMP2B;BGNA;MATN3B;MMP20;MMP24
Molecules associated with elastic fibresMFAP2;LTBP2;MFAP1;MFAP3;EFEMP2;LTBP4;MFAP5;BMP10;MFAP1B
Notch signaling pathwayMFAP2;TUBB3;DTX1;RBPJ;KAT2B;HER9;MAML1;NUMB;RFNG

MFAP5 has several biochemical functions, for example, extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by MFAP5 itself. We selected most functions MFAP5 had, and list some proteins which have the same functions with MFAP5. You can find most of the proteins on our site.

Function Related Protein
extracellular matrix structural constituentLAMA4;COL27A1B;FBN2B;COL24A1;TINAGL1;EFEMP2;FBN1;COL4A4;COL4A5

MFAP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MFAP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of MFAP5.

Saekmose, SG; Schlosser, A; et al. Enzyme-Linked Immunosorbent Assay Characterization of Basal Variation and Heritability of Systemic Microfibrillar-Associated Protein 4. PLOS ONE 8:-(2013).
Akhtar, S; Davies, JR; et al. Ultrastructural immunolocalization of alpha-elastin and keratan sulfate proteoglycan in normal and scoliotic lumbar disc. SPINE 30:1762-1769(2005).
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