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MGST3

  • Official Full Name

    microsomal glutathione S-transferase 3

  • Overview

    This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.
  • Synonyms

    MGST3; microsomal glutathione S-transferase 3; GST III; microsomal glutathione S transferase III; microsomal GST 3; microsomal GST III; MGST3_HUMAN; Microsomal glutathione S transferase 3; Microsomal GST-3; Microsomal GST-III; Microsomal GST3; Microsomal GSTIII; microsomal glutathione S-transferase III; GST-III;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rhesus Macaque
  • Zebrafish
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MGST3-4326HCL Recombinant Human MGST3 293 Cell Lysate HEK293 N/A
Human MGST3-6526HF Recombinant Full Length Human MGST3 Protein, GST-tagged In Vitro Cell Free System GST 152 amino acids
Human MGST3-5311H Recombinant Human MGST3 Protein, GST-tagged Wheat Germ GST
Mouse MGST3-9821M Recombinant Mouse MGST3 Protein Mammalian Cell His
Mouse MGST3-5544M-B Recombinant Mouse MGST3 Protein Pre-coupled Magnetic Beads HEK293
Mouse MGST3-5544M Recombinant Mouse MGST3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL21373BF Recombinant Full Length Bovine Microsomal Glutathione S-Transferase 3(Mgst3) Protein, His-Tagged E.coli expression system His Full Length (1-152)
Homo sapiens (Human) RFL20483HF Recombinant Full Length Human Microsomal Glutathione S-Transferase 3(Mgst3) Protein, His-Tagged E.coli expression system His Full Length (1-152)
Mus musculus (Mouse) RFL778MF Recombinant Full Length Mouse Microsomal Glutathione S-Transferase 3(Mgst3) Protein, His-Tagged E.coli expression system His Full Length (1-153)
Rhesus Macaque MGST3-2767R Recombinant Rhesus monkey MGST3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MGST3-2588R-B Recombinant Rhesus Macaque MGST3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MGST3-2588R Recombinant Rhesus Macaque MGST3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish MGST3-12599Z Recombinant Zebrafish MGST3 Mammalian Cell His
Chicken MGST3-4921C Recombinant Chicken MGST3 Mammalian Cell His
Chicken MGST3-4925C Recombinant Chicken MGST3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MGST3 Related Articles

MGST3 involved in several pathways and played different roles in them. We selected most pathways MGST3 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with MGST3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glutathione metabolismGPX6;GPX2;GSTT1B;GPX5;ODC1;GGCT;GSTT2;GGT6;GSTT1
Metabolism of xenobiotics by cytochrome PGSTM4;CBR1;DHDHL;GSTA5;HSD11B1;GSTT2B;MGST1;MGST1.1;GSTM1
Drug metabolism - cytochrome PGSTT2;ALDH3A1;MGST3;FMO1;FMO6P;ALDH3B2;UGT2A1;UGT1A7C;UGT1A3
Chemical carcinogenesisCYP2E1;CHRNA7;UGT1A1;CYP2B19;GSTM7;CYP2C50;GSTM5;GSTA3;SULT1A1

MGST3 has several biochemical functions, for example, glutathione peroxidase activity, glutathione transferase activity, peroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MGST3 itself. We selected most functions MGST3 had, and list some proteins which have the same functions with MGST3. You can find most of the proteins on our site.

Function Related Protein
glutathione peroxidase activityLTC4S;GPX5;GPX1A;GPX4;GPX7;MGST2;GPX1B;GPX1;GSTT1
glutathione transferase activityGSTM5;GSTZ1;GDAP1;GDAP1L1;GSTM6;HPGDS;GSTA3;EEF1E1;GSTP2
peroxidase activityPTGS1;GPX1B;GPX1A;MPX;EPX;PTGS2B;TPO;GPX5;DUOX2
protein bindingGNB2;TXN;RPS13;AURKAIP1;STX19;KCNA2;TMEM171;RBFOX1;NFASC

MGST3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MGST3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MGST3.

CCNC; Tubb4b; F10; Lin7c; Rmdn3; VAPA; GOLT1B

Weng, ZQ; Greenhaw, J; et al. Mechanisms for epigallocatechin gallate induced inhibition of drug metabolizing enzymes in rat liver microsomes. TOXICOLOGY LETTERS 214:328-338(2012).
Bhattacharya, P; Keating, AF; et al. Protective role for ovarian glutathione S-transferase isoform pi during 7,12-dimethylbenz[a]anthracene-induced ovotoxicity. TOXICOLOGY AND APPLIED PHARMACOLOGY 260:201-208(2012).
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