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MID2

  • Official Full Name

    midline 2

  • Overview

    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
  • Synonyms

    MID2; midline 2; probable E3 ubiquitin-protein ligase MID2; FXY2; RNF60; TRIM1; Midin-2; Midline defect 2; Midline-2; RING finger protein 60; Ring finger protein protein 60; TRIM1_HUMAN; Tripartite motif protein 1; Tripartite motif-containing protein 1; midin 2; OTTHUMP00000023816; OTTHUMP00000023817;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Wheat Germ
  • GST
  • N/A
  • N
  • His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MID2-877H Recombinant Human MID2, GST-tagged E.coli GST C-term-350aa
Human MID2-4318HCL Recombinant Human MID2 293 Cell Lysate HEK293 N/A
Human MID2-4319HCL Recombinant Human MID2 293 Cell Lysate HEK293 N/A
Human MID2-6588HF Recombinant Full Length Human MID2 Protein, GST-tagged In Vitro Cell Free System GST 685 amino acids
Human MID2-5330H Recombinant Human MID2 Protein, GST-tagged Wheat Germ GST
Human MID2-2443H Recombinant Human MID2 Protein, His-tagged E.coli N-His Ser7-Glu258
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MID2 Related Articles

MID2 involved in several pathways and played different roles in them. We selected most pathways MID2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MID2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MID2 has several biochemical functions, for example, ligase activity, microtubule binding, phosphoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MID2 itself. We selected most functions MID2 had, and list some proteins which have the same functions with MID2. You can find most of the proteins on our site.

Function Related Protein
ligase activityTTLL9;RNF144B;UBR5;HECTD1;MARCH9;PRP19;BIRC3;SIAH2;MARCH1
microtubule bindingKIF3C;TPPP;JAKMIP2;KIF1C;NDEL1B;JAKMIP1;CLASP1;GOLSYN;REEP4
phosphoprotein bindingPIH1D1;LRP11;URI1;SRC;SERPINB1A;ARR3;GPRIN1;DPYSL3;PLAT
protein bindingAGPAT4;TBC1D24;BNIP1;RFX6;RAC3;LINC00482;INTS4;MTAP1B;MED11
protein heterodimerization activityTPD52L1;HIST1H4B;SIM2;CD3E;RBP4;TCF4;HAND1;GCLM;BIK
protein homodimerization activitySLC14A2;LRRC41;CHMP4B;ANO6;Fzd4;EPHX2;MAP3K11;GAMT;NKX2-5
zinc ion bindingZFAND5;RPS29;ESR2A;ADAMTS3;PRKCBA;DNAJC21;RNF121;ZIM2;ZNF92

MID2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MID2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MID2.

COX5B; ZNF24; GFI1B; ligA; CEP57L1; DYDC1; TSGA10; TMEM14B; UBE2D4; TCAF1

Miyamoto, M; Furuichi, Y; et al. The high-osmolarity glycerol- and cell wall integrity-MAP kinase pathways of Saccharomyces cerevisiae are involved in adaptation to the action of killer toxin HM-1. YEAST 29:475-485(2012).
Martin, H; Rodriguez-Pachon, JM; et al. Regulatory mechanisms for modulation of signaling through the cell integrity Slt2-mediated pathway in Saccharomyces cerevisiae. JOURNAL OF BIOLOGICAL CHEMISTRY 275:1511-1519(2000).
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