MLANA
-
Official Full Name
MLANA melan-A
-
Overview
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. -
Synonyms
MLANA; melan-A; melanoma antigen recognized by T-cells 1; MART1; antigen LB39-AA; antigen SK29-AA; protein Melan-A; MART-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian cells
- Wheat Germ
- Yeast
- Flag
- GST
- His
- His (Fc)
- Avi
- His|B2M
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- MLANA Related Research Area
MLANA involved in several pathways and played different roles in them. We selected most pathways MLANA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MLANA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
MLANA has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MLANA itself. We selected most functions MLANA had, and list some proteins which have the same functions with MLANA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SNX18;U2AF1;FGF19;HSPA1A;SLX4IP;CCDC6;POLR3F;KCNIP1;AKR7A3 |
MLANA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLANA here. Most of them are supplied by our site. Hope this information will be useful for your research of MLANA.
GPR143; NEDD4; ITCH
- Q&As
- Reviews
Q&As (6)
Ask a questionMLANA can interact with a variety of other proteins, including proteins on mitochondrial membranes, members of the Bcl-2 family, and caspases. These interactions allow it to regulate processes such as mitochondrial dynamics and apoptosis.
Studies have shown that the expression level of MLANA is upregulated in some cancers, which may be related to the occurrence and development of tumors. It could be a potential target for cancer treatment.
Therapeutic strategies for MLANA include inhibiting its expression, inhibiting its interaction with specific proteins, and targeting degradation. These approaches may have potential applications for certain cancer treatments.
The structure of MLANA determines its ability to interact with other proteins on the mitochondrial membrane and its function. The study of its structure can help us understand its function and mechanism of action.
The expression level of MLANA can be regulated in a variety of ways, including transcription, post-transcriptional modification, and degradation. These processes may involve various molecules such as transcription factors, regulatory Rnas, and signal transduction pathways.
MLANA can interact with a variety of proteins on the mitochondrial membrane to regulate the fusion and division of mitochondria, thus maintaining the homeostasia of mitochondria.
Customer Reviews (3)
Write a reviewThe labeling effect is excellent in Western blot, and fluorescent labeling can be performed.
The stability of MLANA is excellent and adaptable under a variety of conditions.
Good expression level and stability in clonal expression.
Ask a Question for All MLANA Products
Required fields are marked with *
My Review for All MLANA Products
Required fields are marked with *
