MMAB
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Official Full Name
methylmalonic aciduria (cobalamin deficiency) cblB type
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Overview
This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found. -
Synonyms
MMAB; methylmalonic aciduria (cobalamin deficiency) cblB type; methylmalonic aciduria (cobalamin deficiency) type B; cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial; ATP:cob(I)alamin adenosyltransferase; cblB; mitochondrial; aquocob(I)alamin vitamin B12s adenosyltransferase; ATP:corrinoid adenosyltransferase; ATR; c-diamide adenosyltransferase; Cob; Cob(I)alamin adenosyltransferase; Cob(I)yrinic acid a; Methylmalonic aciduria type B protein; MGC20496; MMAB_HUMAN; OTTHUMP00000240563; OTTHUMP00000240564;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- MMAB Related Articles
MMAB involved in several pathways and played different roles in them. We selected most pathways MMAB participated on our site, such as Porphyrin and chlorophyll metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMAB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Porphyrin and chlorophyll metabolism | ALAS2;UGT1AB;MMAB;COX15;BLVRA;EPRS;COX10;GUSB;HEPH |
Metabolic pathways | ACSS1;PLA2G10;GNSB;ACOT2;AKR1A1B;AADAT;DHODH;LTC4S;UAP1L1 |
MMAB has several biochemical functions, for example, ATP binding, cob(I)yrinic acid a,c-diamide adenosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MMAB itself. We selected most functions MMAB had, and list some proteins which have the same functions with MMAB. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | CKMA;TPK1;DHX30;SRC;MAP3K11;HIPK3B;CSK;BMPR1BB;ABCG1 |
cob(I)yrinic acid a,c-diamide adenosyltransferase activity |
MMAB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMAB here. Most of them are supplied by our site. Hope this information will be useful for your research of MMAB.
ICT1
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