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MMEL1

Official Full Name

membrane metallo-endopeptidase-like 1
Overview

The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.
Synonyms

MMEL1; membrane metallo-endopeptidase-like 1; membrane metallo endopeptidase like 2 , MMEL2; NEPII; NL1; NL2; SEP; Mel transforming oncogene like 1; MELL1; Membrane metallo endopeptidase like 1; Membrane metallo endopeptidase like 2; MMEL2; Neprilysin 2; Neprilysin Like 1; Soluble secreted endopeptidase; NEP2(m); neprilysin-2; neprilysin II; zinc metallopeptidase; membrane metallo-endopeptidase-like 2; NEP2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rattus norvegicus (Rat)

Source

E.coli expression system
HEK293
In Vitro Cell Free System
Mammalian cells
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MMEL1-1981H	Active Recombinant Human Membrane Metallo-Endopeptidase-Like 1, His-tagged	Mammalian cells	His		Inquiry
Human	MMEL1-384H	Active Recombinant Human MMEL1, His-tagged	Mammalian cells	His		Inquiry
Human	MMEL1-1121HCL	Recombinant Human MMEL1 cell lysate		N/A		Inquiry
Human	MMEL1-5411H	Recombinant Human MMEL1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MMEL1-3484H	Recombinant Human MMEL1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	MMEL1-6395HF	Recombinant Full Length Human MMEL1 Protein, GST-tagged	In Vitro Cell Free System	GST	779 amino acids	Inquiry
Human	MMEL1-3484H-B	Recombinant Human MMEL1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rattus norvegicus (Rat)	RFL19513RF	Recombinant Full Length Rat Membrane Metallo-Endopeptidase-Like 1(Mmel1) Protein, His-Tagged	E.coli expression system	His	Full Length (1-774)	Inquiry

Involved Pathway
Protein Function
Interacting Protein

MMEL1 involved in several pathways and played different roles in them. We selected most pathways MMEL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MMEL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

MMEL1 has several biochemical functions, for example, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MMEL1 itself. We selected most functions MMEL1 had, and list some proteins which have the same functions with MMEL1. You can find most of the proteins on our site.

Function	Related Protein
metalloendopeptidase activity	ADAMDEC1;ADAMTS10;MMP14;MMP2;ADAM10;MMP15;ADAM7;PHEX;ADAM23
zinc ion binding	TRIM15;ZDHHC2;UBR2;ZCWPW1;ZDHHC8B;CXXC1A;TOP3A;CRIP2;Adamts19

MMEL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMEL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMEL1.